Browsing by Author "Balapattabi, Kirthikaa"
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High Salt Loading Increases Brain Derived Neurotrophic Factor in Supraoptic Vasopressin Neurons
Balapattabi, Kirthikaa (2018-03-14)Purpose: Salt loading (SL) upregulates Brain Derived Neurotrophic Factor (BDNF) and causes increased arginine vasopressin (AVP) release from supraoptic nucleus of the hypothalamus (SON). BDNF diminishes or reverses the ... -
Intracellular Chloride Regulation of Supraoptic Vasopressin Neurons during Salt Loading
Balapattabi, Kirthikaa (2019-03-05)Purpose Salt loading (SL) increases intracellular chloride concentration [Cl]i, impairing GABAA inhibition of arginine vasopressin (AVP) neurons in the supraoptic nucleus (SON) of hypothalamus. But the regulatory mechanisms ... -
Regulation of Supraoptic Vasopressin Neurons during Hypernatremia and Hyponatremia
Balapattabi, Kirthikaa (2019-05)This dissertation addresses the regulatory mechanisms of arginine vasopressin (AVP) secretion during salt loading (SL) and liver failure. The experiments focused on AVP neurons located in the supraoptic nucleus (SON) of ... -
Role of Brain Derived Neurotrophic Factor in the Supraoptic nucleus on Response to Salt Loading
Balapattabi, Kirthikaa (2017-03-14)Purpose: Previous studies have shown that Brain Derived Neurotrophic Factor (BDNF) contributes to ionic plasticity of vasopressin neurons from the supraoptic nucleus of the hypothalamus (SON) in response to 7 days of salt ... -
Sex Specific Effects of Salt Loading on GABAA Responses in Oxytocin Neurons from the Supraoptic Nucleus
Brock, Courtney; Bachelor, Martha; Little, Joel; Farmer, George; Balapattabi, Kirthikaa; Cunningham, Joseph (2022)Arginine Vasopressin (AVP) and oxytocin (OXY) contribute to body fluid balance homeostasis. Salt loading (2% NaCl for 7 days) increases both AVP and OXY release in rats. The chronic increase in AVP release is associated ...