Browsing by Author "Gaidhani, Nikhil"

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Increased duration of isoflurane exposure reduces cerebral infarct and improves neurological function in focal cerebral ischemia in rats

Gaidhani, Nikhil (2016-03-23)

Isoflurane is a widely used gas anesthetic for surgical procedure in rodents. Using a rodent model of transient ischemic stroke (transient midcerebral artery occlusion; tMCAO) our laboratory has demonstrated that longer ...
Positive allosteric modulation of alpha7 nicotinic acetylcholine receptors as a novel approach to treatment of ischemic stroke

Gaidhani, Nikhil (2018-03-14)

Ischemic stroke is a leading cause of disability and death worldwide. Despite substantial investments in developing anti-stroke medicines, clinically effective pharmacological treatments remain inadequate. Clinical utility ...