Browsing by Author "Sabnis, Nirupama"

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Lipoprotein Drug Delivery Initiative: A Translational research program employing the HDL and HDL mimetic drug delivery platform.

Sabnis, Nirupama (2020)

Reconstituted (synthetic) lipoproteins and lipoprotein mimetics have been recognized as a superior biocompatible, targeted drug-delivery platform and thus have great potential in the treatment of a number of diseases. Our ...
Reprogramming of B16-F10 melanoma-educated macrophages by STING agonists loaded in mannose-decorated reconstituted high density lipoprotein nanoparticles.

Dossou, Akpedje Serena; Kapic, Ammar; Mamo, Lois; Sabnis, Nirupama; Lacko, Andras; Fudala, Rafal (2022)

Purpose: Representing a large portion of tumor-infiltrating cells, tumor-associated macrophages (TAMs) have the potential to mediate an immune response against the tumor. Instead, they are educated by the tumor microenvironment ...
Targeted delivery of α-Mangostin to Prostate Cancer Cells Utilizing Reconstituted High-Density Lipoprotein Nanoparticles

Kapic, Ammar; Dossou, Akpedje; Lacko, Andras; Sabnis, Nirupama; Petty, Roland; Fudala, Rafal (2022)

Purpose: Androgen deprivation therapy remains the primary treatment for inhibiting the progression of prostate cancer (PCa). However, depletion of systemic androgens enhances the development of androgen independence resulting ...