Browsing by Author "Yu, Yu"
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Biological Characteristics of Lens Epithelial Cells from Grx1 and Grx2 Double Knockout Mice
Zhang, Jinmin; Yu, Yu; Lal, Kevin; Dang, Terry; Ezugwu, Chimdindu; Tran, Myhoa; Wu, Hongli; 0000-0001-6424-0642 (Lal, Kevin) (2022)Purpose: Glutaredoxins are glutathione (GSH) dependent enzymes that play an important role in repairing oxidized proteins, preventing subsequent protein misfolding and disrupting protein aggregation. The Grx system has two ... -
Decoding the anti-cataractogenic mechanism of grapes via a systemic pharmacology approach
Yu, Yu (2019-03-05)Introduction: Our previous study has indicated that grapes may be able to protect against in vivo ultraviolet B (UV-B) radiation-induced cataract. To better understand the mechanism of action of grapes in cataract prevention, ... -
Retina-Targeted Estrogen Prodrug: A New Concept for Retinal Protection
Lal, Kevin; Yu, Yu; Zhang, Jinmin; Tran, Myhoa; Ezugwu, Chimdindu; Prokai, Katalin; Liu, Yang; Wu, Hongli; 0000-0001-6424-0642 (Lal, Kevin) (2022)Retinal injury due to excessive light exposure during military duties often results in serious vision damage to soldiers including irreversible loss of visual function. However, therapeutic interventions that can promote ...