• Phenotype of Neurons in the Nucleus Tractus Solitarius Labeled using an Optogenetic Construct with a CaMKIIa Promoter 

  Lopez, Jackson D. (2017-05)

  Optogenetics is a very useful technique used to activate or inhibit specific cells of interest in specific brain regions. The purpose of this study was to determine the phenotype of cells within the nucleus tractus solitarius ...

• Clinical Significance of Annexin A2 in Predicting Poor Prognosis in African American Women with Triple-Negative Breast Cancer 

  Gibbs, Lee D. (2017-05)

  Triple-negative breast cancers (TNBC) are identified by the absence of these three major receptors that drive most breast cancer subtypes. TNBC is the most aggressive breast cancer subtype and studies have shown that the ...

• Pyruvate-enriched Preservation of Machine Perfused Kidneys 

  Omar, Salma K. (2020-05)

  Purpose: Kidney transplantation remains the gold-standard treatment for patients diagnosed with end-stage renal disease (ESRD). However, the demand for donors currently far outpaces the supply. Kidneys donated after cardiac ...

• The Validation of the RapidHIT ID System for Human Identification 

  Campos, Gemma R. (2020-05)

  Forensic scientists routinely employ short tandem repeat (STR) typing as a means to identify or exclude individuals as the donors of biological evidence at crime scenes. Despite developments in automation of STR typing ...

• Alternative procedure for DNA recovery from cartridges and casings 

  Bettex, Kelsey D. (2020-05)

  Both unfired and fired ammunition recovered from a crime scene are useful in connecting a crime to a specific firearm, however its use in identifying individuals is less common due to low-level or degraded DNA present. ...

• Typing Highly Degraded DNA Using Target Enrichment 

  Kieser, Rachel E. (2020-05)

  Forensic genetic profiling is the process of targeting unique positions within the human genome for identity testing of biological DNA evidence. Forensic profiling of highly degraded DNA samples is one of the primary ...

• Validation of the PowerPlex(R) Fusion 6C System and Alternate Robotic Methods on the Hamilton MICROLAB(R) STAR 

  Smith, Briana N. (2020-05)

  Internal validations are done in forensic laboratories to ensure the methods and procedures are working as expected. For this internship practicum, I conducted an internal validation of Promega's PowerPlex(R) Fusion 6C ...

• Optimization and Evaluation of qPCR Duplex Assay for mtDNA Copy Number Quantification 

  Johnson, Gretchen A. (2020-05)

  Purpose: The mitochondrial genome (mtDNA) encodes thirteen essential proteins in oxidative phosphorylation, the cell's primary energy-generating process. Depending on the cell type and stage of development, each cell ...

• Variation in Mitochondrial DNA Heteroplasmy from Blood, Buccal, and Hair Samples 

  Colon, Natalie S. (2020-05)

  Mitochondrial DNA (mtDNA) sequence variation has important forensic implications. This research assesses five subjects for variation in point heteroplasmy (PHP) using blood, buccal, and head hair from five scalp sites. ...

• The Role of Angiotensin Converting Enzyme 1 within the Median Preoptic Nucleus Following Chronic Intermittent Hypoxia 

  Faulk, Katelynn E. (2016-08)

  These experiments focused on the importance of the brain renin-angiotensin system (RAS) in hypertension caused by a chronic intermittent hypoxia (CIH) model of the hypoxemia associated with sleep apnea. In the CIH model, ...

• Pyruvate Intervention for Brain Injury Inflicted by Cardiac Arrest-Resuscitation 

  Nguyen, Anh Q. (2016-05)

  Fewer than 10% of the 360,000 people who suffer out-of-hospital cardiac arrest annually in the U.S. survive to hospital discharge. Many suffer brain injuries that greatly affect their daily activities and quality of life. ...

• Positive allosteric modulation of alpha7 nicotinic acetylcholine receptors as a novel approach to treatment of ischemic stroke 

  Gaidhani, Nikhil, M. (2017-12)

  Ischemic cerebral stroke is a leading cause of disability and death worldwide. Despite substantial investments in developing anti-stroke medicines, clinically effective pharmacological treatments remain inadequate. Clinical ...

• Creation of a biotechnology discovery platform for fighting the transmission of vector-borne infectious diseases 

  Wang, Huanyu (2017-08)

  Vector-borne diseases have become a global pandemic threatening 40% of the world's population with infectious diseases like malaria and Lyme disease becoming ever more of a concern. The best treatment of vector-borne ...

• An Analysis of Employee Engagement within the Heart and Lung Transplant and Pulmonary Research Department of the Baylor Scott and White Research Institute at Dallas, TX. 

  Lee, Daniel J. (2018-12)

  Introduction: Employee engagement is an important construct to measure, with positive employee engagement linked to favorable business outcomes such as increased customer satisfaction, increased productivity, and decreased ...

• Retinal ganglion cell death in acute and chronic models of glaucoma: Is the degeneration subtype specific? 

  Daniel. Steffi (2018-12)

  Glaucoma, the world's leading cause of irreversible blindness, is a group of optic neuropathies with multifactorial etiologies that lead to optic nerve degeneration and retinal ganglion cell (RGC) death, severing the ...

• Establishment of Animal Models of Mycoplasma pnumoniae pneumonia and Staphylococcus arueus osteomyelitis 

  Chikelue, Calvin I. (2018-12)

  Animal models are useful tools in the study and development of clinical solutions to pathogens. Our focus is on two clinically relevant bacterium: Mycoplama pnumoniae which can lead to community acquired pneumonia and ...

• The Effect of Aquatic Therapy on Patients with a Complete Spinal Cord Injury in the In-Patient Rehabilitation Setting 

  Bailey, David G. (2018-12)

  Although aquatic therapy has been proven to be effective in the treatment of incomplete spinal cord injuries, it is consistently underutilized in the spinal cord injury patient population. Approximately 56% (n=57) of the ...

• The Picture of C. difficile epidemic and non-epidemic ribotypes: are there differences in virulence? 

  Vitucci, John C. (2019-12)

  The purpose of these studies was to determine if the epidemic ribotype of C. difficile (now Clostridioides difficile) was more virulent than non-epidemic ribotypes, to ascertain whether clinics contribute to community-acquired ...

• Use of Bedside Point-of-Care Ultrasound (POCUS) among Healthcare Professionals in the Emergency Department 

  Wiemann, Natalia M. (2019-12)

  Point of Care Ultrasound (POCUS) use has become increasingly prominent in emergency departments (ED's) over the past 30 years. With the emergence of this technology, many healthcare providers are becoming more aware of the ...

• Remote Recruitment and Data Collection and Its Effect on Demographics and Outcome Variable Scores 

  Cooper, Savannah B. (2019-12)

  BACKGROUND: Technology continues to push different aspects of research forward, including new recruitment methods and updated data collection/management. More and more, researchers are beginning to use social media as a ...

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