Browsing School of Biomedical Sciences by Title
Now showing items 720-739 of 889
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T-Helper Cell Responses in Lungs After Immunization and Chronic Respiratory Disease; And Their Association With Pulmonary Inflammation
(2001-05-01)The purpose of these studies was to characterize T helper cell responses in the lungs of mice after immunization and chronic respiratory infection. CD4+ T cells were the major population of T cells resident in the lung in ... -
TAAR1-dependent astrocyte dysregulation during HAND and METH exposure
(2018-12)Excitatory amino-acid transporter (EAAT)-2 is predominantly expressed in astrocytes and clears glutamate from tripartite synapses preventing excitotoxicity. EAAT- 2 dysregulation occurs during human immunodeficiency virus ... -
TAARgeting Astrogliosis and Mitochondrial Dysfunction during METH Exposure and HIV-relevant Neuroinflammation
(2017-12-01)As a popular psychostimulant, methamphetamine (METH) use leads to long-lasting, strong euphoric effects. METH exacerbates the severity and onset of HIV-associated neurocognitive disorders (HAND), which affect 30-70% of the ... -
Targeted Nanoparticles for the Treatment of Neuroblastoma
(2011-05-01)Neuroblastoma (NB) is one of the most frequently diagnosed tumors in infants and children. However, the mechanism by which it is initiated and subsequently develops on the molecular and cellular level is yet to be fully ... -
Testing Minimum Ultraviolet Light Exposures to Effectively Remove Contaminating DNA for Use in Forensics
(2005-08-01)This study introduces a solar lamp UV light source, for the purpose of removing contaminating DNA in direct relation to forensic testing. The study attempts to demonstrate what level of decontamination occurs from sun lamp ... -
Testosterone Replacement Therapy: Role in Modulating Oxidative Stress within the Entorhinal Cortex
(2021-05)Sleep apnea affects approximately a quarter of all Americans. The effects of sleep apnea involve a decrease in testosterone levels, along with an increased rate of hypertension, stroke, and coronary heart disease. Chronic ... -
TGF Beta 2 and Gremlin Signaling Pathways Regulate Extracellular Matrix Changes in TM Cells: Implications for Glaucoma
(2011-05-01)Purpose: Glaucoma is a leading cause of blindness worldwide. The leading risk factor is elevated intraocular pressure (IOP) due to fibrotic changes in the trabecular meshwork (TM) tissue. The profibrotic cytokine TGFβ2 is ... -
TGFβ Signaling and the Formation of Cross-Linked Actin Networks (CLANs) in Human Trabecular Meshwork Cells
(2016-05-01)Glaucoma is the leading cause of irreversible vision loss and blindness worldwide. One of the major risk factors for glaucoma is increased intraocular pressure (IOP); however there is little understanding of the initial ... -
The 6' and 7' Residue of the Second Transmembrane Domain of Ligand-Gated Ion Channels Influence Gating and Picrotoxin Sensitivity
(2005-07-01)Gonzales, Eric B., The 6’ and 7’ residue of the second transmembrane domain of ligand-gated ion channels influence gating and picrotoxin sensitivity. Doctor of Philosophy (Pharmacology and Neuroscience), July 2005, pp213, ... -
The Acute and Chronic Effects of Beta Blockade on Dynamic Exercise Performance and Cardiac Adaptation to Dynamic Exercise Training
(1998-06-01)Widespread use of beta-adrenergic blocking agents as treatments for hypertension, ischemic heart disease and postmyocardial infarction has raised many questions concerning the effect of these drugs during exercise. Since ... -
The Analysis of Current Recruitment Methods: Measuring the Potential of Social Media in Clinical Research Trials
(2015-12-01)Clinical research has an important role as the intermediate step before an investigational drug or procedure is approved for distribution to the public. Before an investigational drug is approved, researchers must prove ... -
The Applicability of Whole Genome Amplification to Minute Quantities of DNA for Forensic Use
(2004-08-01)This research study was performed at DNAPrint™ in Sarasota. FL. DNAPrint™ is a private laboratory specializing in Single Nucleotide Polymorphism (SNP) technology. Through the use of this technology, they have been able to ... -
The Association between Obesity, Cognition, and Visual Function
(2011-05-01)Purpose: Obesity is an adverse health condition characterized by excessive weight gain. Aside from the pathological conditions most commonly associated with obesity, recent epidemiological studies have suggested that obesity ... -
The Association of Health Literacy with the Management of Type 2 Diabetes
(2017-12-01)Introduction: Type 2 Diabetes (T2D) is a chronic metabolic disease characterized by high blood glucose levels in the blood. It is associated with microvascular and macrovascular complications which can lead to potential ... -
The Avian Influenza Pandemic and Physicians' Perception of Preparedness
(2008-05-01)Oberdorfer, Joseph R., The avian influenza pandemic and physicians’ perception of preparedness. Master of Science (Biomedical Sciences) May, 2008, 77 pp., 5 tables, 3 figures, bibliography 84 titles. Prepared physicians ... -
The Cephalic Vein: Anatomical Study and Evaluation of the Coracoid Process as a Topographical Bony Landmark
(2020-05)INTRODUCTION. Clinicians require accurate anatomical information when gaining central venous access. Despite the cephalic vein cut down (CVCD) procedure being described as a superior choice to other methods, the cephalic ... -
The Characterization of T Cell Responses Along the Respiratory Tract
(2004-05-01)Ivey, James A., The Characterization of T Cell Responses Along the Respiratory Tract. Masters (Immunology). May, 2004. 63 pages. 2 tables, 10 figures. 55 titles. This research converged on T cell responses to respiratory ... -
The Comparison of Four DNA Extraction Techniques From Blood for Forensic Application
(2003-08-01)The results of the phenolphthalein sensitivity study indicate that dilutions of blood down to a 1:1,000 level can be detected with the phenolphthalein presumptive test. Even though this value is not as sensitive as reported ... -
The Development and Evaluation of an Oligonucleotide Probe for Use in Quantifying Human Mitochondrial DNA Using the Quantiblot Human DNA Identification Kit
(2003-07-01)Cooksley, Joseph David, The Development and Evaluation of an Oligonucleotide Probe for Use in Quantifying Human Mitochondrial DNA Using the Quantiblot Human DNA Identification Kit. Master of Science (Forensic Genetics), ... -
The Development of a Core Set of Standard Operating Procedures in Order to Promote Quality, Consistency, and Efficiency in the Conduct of Oncology Clinical Research at the University of Texas Southwestern
(2005-12-01)There is an increasing need for standardization of tools and methods involved in the management of complex study tasks from study set-up and initiation, through subject recruitment and treatment, to study closure. Standardizing ...