Now showing items 1-3 of 3
Identification of novel alternative splicing biomarkers for breast cancer with LC/MS/MS and RNA-Seq
(BioMed Central Ltd., 2020-12-03)
Background: Alternative splicing isoforms have been reported as a new and robust class of diagnostic biomarkers. Over 95% of human genes are estimated to be alternatively spliced as a powerful means of producing functionally ...
Identification of long non-coding RNA-related and -coexpressed mRNA biomarkers for hepatocellular carcinoma
(BioMed Central Ltd., 2019-01-31)
Background: While changes in mRNA expression during tumorigenesis have been used widely as molecular biomarkers for the diagnosis of a number of cancers, the approach has limitations. For example, traditional methods do ...
A Precision Medicine Approach to Treating Alzheimer's Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials
(IOS Press, 2021-05-18)
Background: The REFLECT trials were conducted to examine the treatment of mild-to-moderate Alzheimer's disease utilizing a peroxisome proliferator-activated receptor gamma agonist. Objective: To generate a predictive ...