Now showing items 1-5 of 5
Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans
Mitochondrial function has been implicated and studied in numerous complex age-related diseases. Understanding the potential role of mitochondria in disease pathophysiology is of importance due to the rise in prevalence ...
The Health & Aging Brain among Latino Elders (HABLE) study methods and participant characteristics
(Wiley Periodicals, LLC, 2021-06-21)
Introduction: Mexican Americans remain severely underrepresented in Alzheimer's disease (AD) research. The Health & Aging Brain among Latino Elders (HABLE) study was created to fill important gaps in the existing literature. ...
Variations of the lung microbiome and immune response in mechanically ventilated surgical patients
Mechanically ventilated surgical patients have a variety of bacterial flora that are often undetectable by traditional culture methods. The source of infection in many of these patients remains unclear. To address this ...
Identification of novel alternative splicing biomarkers for breast cancer with LC/MS/MS and RNA-Seq
(BioMed Central Ltd., 2020-12-03)
Background: Alternative splicing isoforms have been reported as a new and robust class of diagnostic biomarkers. Over 95% of human genes are estimated to be alternatively spliced as a powerful means of producing functionally ...
Identification of long non-coding RNA-related and -coexpressed mRNA biomarkers for hepatocellular carcinoma
(BioMed Central Ltd., 2019-01-31)
Background: While changes in mRNA expression during tumorigenesis have been used widely as molecular biomarkers for the diagnosis of a number of cancers, the approach has limitations. For example, traditional methods do ...