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Dissecting the Role of Protein Kinase C-Epsilon in Breast Cancer
Protein kinase C-epsilon (PKCε) has pro-tumor functions in many cancers including breast cancer. The purpose of this dissertation is to understand the role of PKCε in fundamental processes that are associated with breast ...
Function and Regulation of the Natural Killer Cell Receptor 2B4 (CD244)
The purpose of these studies was to investigate two issues related to the natural killer (NK) cell receptor, 2B4 (CD244) – its in vivo function and transcriptional regulation. In previous in vitro studies, ligation of 2B4 ...