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Dissecting the Role of Protein Kinase C-Epsilon in Breast Cancer
(2013-12-01)
Protein kinase C-epsilon (PKCε) has pro-tumor functions in many cancers including breast cancer. The purpose of this dissertation is to understand the role of PKCε in fundamental processes that are associated with breast ...
Characterization of the Bradykinn Receptor in Human Corneal Epithelium
(1997-08-01)
Wiernas, Terry Kirkham, Characterization of the Bradykinin Receptor in Human Corneal Epithelium. Doctor of Philosophy (Biomedical Sciences), August, 1997, 255 pp., 5 tables, 39 figures, references, 137 titles. Bradykinin ...
Function and Regulation of the Natural Killer Cell Receptor 2B4 (CD244)
(2005-05-01)
The purpose of these studies was to investigate two issues related to the natural killer (NK) cell receptor, 2B4 (CD244) – its in vivo function and transcriptional regulation. In previous in vitro studies, ligation of 2B4 ...
Aging of the Thymic Epithelial Progenitor Pool is Determined by the p63-FoxN1 Regulatory Axis
(2015-05-01)
The immune system is composed of various effector cells and molecules that must work in concert in order to protect the body against infections, auto-reaction, and tumor occurrence. These responses can be divided into two ...
Auditory Impairment and Falls: Investigating the Link Between Hearing Loss and Falls among Elderly Individuals
(2013-08-01)
Recent studies show that hearing acuity correlates with postural balance, a prerequisite for mobility, and impaired hearing is associated with greater risk for falls. A possible connection between impaired hearing and falls ...