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Atrophied thymus, a tumor reservoir for harboring melanoma cells
(2018-12-01)
Tumor metastatic relapse is the major cause of cancer-associated mortality. Metastatic relapse is believed to arise from quantities of tumor cells that are below detectable thresholds, which are able to resist radio/chemotherapy ...
A Survey of Anticoagulation Non-Adherence in Emergency Department Patients Presenting with Atrial Fibrillation
(2017-12-01)
Introduction: Patients with atrial fibrillation are at an increased risk of stroke. As part of stroke prevention, these patients are prescribed anticoagulants. The Emergency Medicine Department at the University of Texas ...
“Ecstasy” to Addiction: Mechanistic and Reinforcing Effects of Synthetic Cathinone Analogs of MDMA
(2017-05-01)
Following widespread scheduling, many synthetic cathinone compounds have been diverted from “bath salts” to “Ecstasy” tablets or “Molly” powder formulations in addition to or in lieu of 3,4-methylenedioxymethamphetamine ...
Factors that Impact Patient Enrollment in Clinical Trials
(2014-12-01)
Introduction: Medical progress, now more than ever, demands clinicians to provide tangible proof over sound hypotheses. This is where clinical research steps in as a combatant to the unknown provoked by logical theories ...
Human Blood versus Two Commercially Available Blood Substitutes: A Comparative Analysis
(2016-05-01)
The experiments included in this research were conducted in order to compare expired human blood and two commercially available synthetic blood spatter products (Arrowhead Forensics Spatter Blood and Evident® Crime Scene ...
Role of Adenosine in Acute Hibernation of Guinea-Pig Myocardium
(1995-08-01)
Gao, Zhi-Ping, Role of Adenosine in Acute Hibernation of Guinea-Pig Myocardium Doctor of Philosophy (Biomedical Sciences), August, 1995; 111 pp; 3 tables; 15 figures, bibliography, 158 titles. Myocardial hibernation is a ...
Pathological Mechanisms of Retinal Ischemia/Reperfusion Injury and Potential Targets of Neuroprotection
(2015-12-01)
Neurodegenerative diseases trigger a cascade of pathological mediators including significant accumulation of reactive oxygen species (ROS) and chronic neuroinflammation resulting in widespread neuronal loss. We can effectively ...
Next-Generation Sequencing of Culture Negative Bronchoalveolar Lavage Reveals the Presence of Potentially Pathogenic Microorganisms
(2015-08-01)
Patients undergoing mechanical ventilation are at increased risk for developing nosocomial pneumonia. Traditionally, the diagnosis of pneumonia has relied on the identification of an etiologic agent by the hospital pathology ...
Trace amine associated receptor 1 (TAAR1), a novel astrocyte receptor for METH-mediated neurotoxicity in HIV-1-associated neurocognitive disorders (HAND)
(2015-05-01)
This dissertation explores the role of astrocyte trace amine associated receptor 1 (TAAR1), a novel G-protein coupled receptor (GPCR), in modulating the effects of methamphetamine (METH) on astrocyte-mediated excitotoxicity, ...