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Intravenous Pyruvate to Prevent Renal Injury Following Cardiac Arrest and Resuscitation
Introduction: Cardiac arrest followed by resuscitation and recovery of spontaneous circulation (ROSC) produces systemic ischemia reperfusion (I/R), affecting all internal organs, including the kidney. This type of stress ...
Intermittent hypoxia induced opioidergic protection of the heart
Normobaric intermittent hypoxia conditioning (IHC) induces a robust cardioprotected phenotype in dogs that is remarkably resistant to ischemia and reperfusion induced myocardial infarction and lethal arrhythmias. Previous ...
Intravenous pyruvate to protect heart and brain during closed-chest resuscitation and recovery from cardiac arrest
Cardiac arrest is a leading cause of death in the United States and Western Europe. Cardiopulmonary resuscitation (CPR) is the only means of sustaining the victim until application of defibrillatory countershocks. Although ...