This collection is limited to articles published under the terms of a creative commons license or other open access publishing agreement since 2016. It is not intended as a complete list of the author's works.

Recent Submissions

  • NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis 

    Wang, Hao; Zhao, Peiqi; Zhang, Ying; Chen, Zhen; Bao, Han; Qian, Wenqi; Wu, Jian; Xing, Zhenqiu; Hu, Xiaowei; Jin, Kunlin; Zhuge, Qichuan; Yang, Jianjing; 0000-0002-1336-348X (Jin, Kunlin) (Springer Nature, 2023-08-16)
    Cell fate and proliferation ability can be transformed through reprogramming technology. Reprogramming glioblastoma cells into neuron-like cells holds great promise for glioblastoma treatment, as it induces their terminal ...
  • Mitochondria and Neurodegenerative Diseases: A New Hotspot 

    Li, Ang; Cao, Shuqin; Jin, Kunlin; Su, Huanxing; 0000-0002-1336-348X (Jin, Kunlin) (Aging and Disease, 2023-05-10)
    Growing evidence suggests that the prevalence of neurodegenerative diseases (NDs) is on the rise with the aged population with substantially overlapping clinical and pathological features. The journal "Aging & Disease" ...
  • Aging During the Pandemic: Untangling the Complexities of COVID-19 and Geriatric Care 

    Su, Kaimeng; Jin, Kunlin; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2023-05-16)
    The COVID-19 pandemic has posed unprecedented challenges to the global healthcare system, with the elderly population being particularly vulnerable. This comprehensive review synthesizes the findings from publications in ...
  • QEEG Signatures are Associated with Nonmotor Dysfunctions in Parkinson's Disease and Atypical Parkinsonism: An Integrative Analysis 

    Liu, Hailing; Huang, Zifeng; Deng, Bin; Chang, Zihan; Yang, Xiaohua; Guo, Xinfang; Yuan, Feilan; Yang, Qin; Wang, Liming; Zou, Haiqiang; Li, Mengyan; Zhu, Zhaohua; Jin, Kunlin; Wang, Qing; 0000-0002-1336-348X (Jin, Kunlin) (Aging and Disease, 2023-02-24)
    Parkinson's disease (PD) and atypical parkinsonism (AP), including progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), share similar nonmotor symptoms. Quantitative electroencephalography (QEEG) can be ...
  • A Reliable Nonhuman Primate Model of Ischemic Stroke with Reproducible Infarct Size and Long-term Sensorimotor Deficits 

    Lin, Xiao; Wang, Hua; Huang, Shengwei; Chen, Lefu; Yang, Su; Zhao, Peiqi; Lin, Zhongxiao; Yang, Jianjing; Ruan, Linhui; Ni, Haoqi; Wang, Kankai; Wen, Min; Jin, Kunlin; Zhuge, Qichuan; 0000-0002-1336-348X (Jin, Kunlin) (Aging and Disease, 2023-02-24)
    A nonhuman primate model of ischemic stroke is considered as an ideal preclinical model to replicate various aspects of human stroke because of their similarity to humans in genetics, neuroanatomy, physiology, and immunology. ...
  • Editorial: The NLRP3 inflammasome-mediated neuroinflammation and its related mitochondrial impairment in neurodegeneration 

    Deng, Chao; Cai, Xiang; Wang, Qing; Jin, Kunlin; 0000-0002-1336-348X (Jin, Kunlin) (Frontiers Media S.A., 2023-01-31)
  • Transplantation of ACE2(-) Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia 

    Leng, Zikuan; Zhu, Rongjia; Hou, Wei; Feng, Yingmei; Yang, Yanlei; Han, Qin; Shan, Guangliang; Meng, Fanyan; Du, Dongshu; Wang, Shihua; Fan, Junfen; Wang, Wenjing; Deng, Luchan; Shi, Hongbo; Li, Hongjun; Hu, Zhongjie; Zhang, Fengchun; Gao, Jinming; Liu, Hongjian; Li, Xiaoxia; Zhao, Yangyang; Yin, Kan; He, Xijing; Gao, Zhengchao; Wang, Yibin; Yang, Bo; Jin, Ronghua; Stambler, Ilia; Lim, Lee Wei; Su, Huanxing; Moskalev, Alexey; Cano, Antonio; Chakrabarti, Sasanka; Min, Kyung-Jin; Ellison-Hughes, Georgina; Caruso, Calogero; Jin, Kunlin; Zhao, Robert Chunhua; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2020-03-09)
    A coronavirus (HCoV-19) has caused the novel coronavirus disease (COVID-19) outbreak in Wuhan, China. Preventing and reversing the cytokine storm may be the key to save the patients with severe COVID-19 pneumonia. Mesenchymal ...
  • Traditional Chinese Medicine and Western Medicine Share Similar Philosophical Approaches to Fight COVID-19 

    Zhao, Fangfang; Yang, Zhenhong; Wang, Ningqun; Jin, Kunlin; Luo, Yumin; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2021-08-01)
    Though disciplines in the same field, modern medicine (Western medicine) and traditional medicine (Traditional Chinese medicine, TCM) have been viewed as two distinct and divergent fields of medicine and thus differ greatly ...
  • Recent Progress in Vascular Aging: Mechanisms and Its Role in Age-related Diseases 

    Xu, Xianglai; Wang, Brian; Ren, Changhong; Hu, Jiangnan; Greenberg, David A.; Chen, Tianxiang; Xie, Liping; Jin, Kunlin; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2017-07-21)
    As with many age-related diseases including vascular dysfunction, age is considered an independent and crucial risk factor. Complicated alterations of structure and function in the vasculature are linked with aging hence, ...
  • The Pathogenetic Dilemma of Post-COVID-19 Mucormycosis in India 

    Chakrabarti, Sankha Shubhra; Kaur, Upinder; Aggarwal, Sushil Kumar; Kanakan, Ahalya; Saini, Adesh; Agrawal, Bimal Kumar; Jin, Kunlin; Chakrabarti, Sasanka; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2022-02-01)
    There has been a surge of mucormycosis cases in India in the wake of the second wave of COVID-19 with more than 40000 cases reported. Mucormycosis in patients of COVID-19 in India is at variance to other countries where ...
  • Rapidly Progressive Dementia with Asymmetric Rigidity Following ChAdOx1 nCoV-19 Vaccination 

    Chakrabarti, Sankha Shubhra; Tiwari, Ashutosh; Jaiswal, Sumit; Kaur, Upinder; Kumar, Ishan; Mittal, Amit; Singh, Anup; Jin, Kunlin; Chakrabarti, Sasanka; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2022-06-01)
  • SDF-1/CXCR7 Chemokine Signaling is Induced in the Peri-Infarct Regions in Patients with Ischemic Stroke 

    Zhang, Yu; Zhang, Hongxia; Lin, Siyang; Chen, Xudong; Yao, Yu; Mao, XiaoOu; Shao, Bei; Zhuge, Qichuan; Jin, Kunlin; 0000-0002-1336-348X (Jin, Kunlin); 0000-0003-1594-6707 (Zhang, Hongxia) (JKL International, 2018-04-01)
    Stromal-derived factor-1 (SDF-1, also known as CXCL12) and its receptors CXCR4 and CXCR7 play important roles in brain repair after ischemic stroke, as SDF-1/ CXCR4/CXCR7 chemokine signaling is critical for recruiting stem ...
  • Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging 

    Zhang, Hongxia; Jin, Kunlin; 0000-0002-1336-348X (Jin, Kunlin); 0000-0003-1594-6707 (Zhang, Hongxia) (MDPI, 2020-03-11)
    People are living longer than ever. Consequently, they have a greater chance for developing a functional impairment or aging-related disease, such as a neurodegenerative disease, later in life. Thus, it is important to ...
  • The Prognostic Value of Serum Cytokines in Patients with Acute Ischemic Stroke 

    Li, Xianmei; Lin, Siyang; Chen, Xiaoli; Huang, Wensi; Li, Qian; Zhang, Hongxia; Chen, Xudong; Yang, Shaohua; Jin, Kunlin; Shao, Bei; 0000-0002-1336-348X (Jin, Kunlin); 0000-0002-0405-0887 (Yang, Shaohua); 0000-0003-1594-6707 (Zhang, Hongxia) (JKL International, 2019-06-01)
    The inflammatory response is an unavoidable process and contributes to the destruction of cerebral tissue during the acute ischemic stroke (AIS) phase and has not been addressed fully to date. Insightful understanding of ...
  • Of Cross-immunity, Herd Immunity and Country-specific Plans: Experiences from COVID-19 in India 

    Chakrabarti, Sankha Shubhra; Kaur, Upinder; Singh, Anup; Chakrabarti, Suddhachitta; Krishnatreya, Manigreeva; Agrawal, Bimal Kumar; Mittal, Amit; Singh, Amit; Khanna, Rahul; Gambhir, Indrajeet Singh; Jin, Kunlin; Chakrabarti, Sasanka; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2020-12-01)
    India has witnessed a high number of COVID-19 cases, but mortality has been quite low, and most cases have been asymptomatic or mild. In early April, we had hypothesized a low COVID-19 mortality in India, based on the ...
  • Metformin, Rapamycin, or Nicotinamide Mononucleotide Pretreatment Attenuate Cognitive Impairment After Cerebral Hypoperfusion by Inhibiting Microglial Phagocytosis 

    Yu, Mengdi; Zheng, Xiaoying; Cheng, Fangyu; Shao, Bei; Zhuge, Qichuan; Jin, Kunlin; 0000-0002-1336-348X (Jin, Kunlin) (Frontiers Media S.A., 2022-06-13)
    Vascular cognitive impairment (VCI) is the second leading form of dementia after Alzheimer's disease (AD) plaguing the elder population. Despite the enormous prevalence of VCI, the biological basis of this disease has been ...
  • Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress 

    Gao, Huimin; Chen, Zhaoyu; Fu, Yongmei; Yang, Xiaoyan; Weng, Ruihui; Wang, Rui; Lu, Jianjun; Pan, Mengqiu; Jin, Kunlin; McElroy, Chris; Tang, Beisha; Xia, Ying; Wang, Qing; 0000-0002-1336-348X (Jin, Kunlin) (Springer Nature, 2016-09-29)
    The nuclear orphan receptor, Nur77 plays important roles in neuroimflammation, apoptosis, and dopaminergic neurodegeneration. We conducted a further mechanistic investigation into the association of Nur77 with cell death. ...
  • A Microcirculatory Theory of Aging 

    Jin, Kunlin; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2019-06-01)
    Aging is the progressive decline of physiological functions necessary for survival and reproduction. In gaining a better understanding of the inevitable aging process, the hope is to preserve, promote, or delay healthy ...
  • Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion 

    Zhang, Lin-Yuan; Pan, Jiaji; Mamtilahun, Muyassar; Zhu, Yuan; Wang, Liping; Venkatesh, Ashwin; Shi, Rubing; Tu, Xuanqiang; Jin, Kunlin; Wang, Yongting; Zhang, Zhijun; Yang, Guo-Yuan; 0000-0002-1336-348X (Jin, Kunlin) (Ivyspring International Publisher, 2020-01-01)
    Microglial activation participates in white matter injury after cerebral hypoperfusion. However, the underlying mechanism is unclear. Here, we explore whether activated microglia aggravate white matter injury via complement ...
  • Limb Ischemic Conditioning Improved Cognitive Deficits via eNOS-Dependent Augmentation of Angiogenesis after Chronic Cerebral Hypoperfusion in Rats 

    Ren, Changhong; Li, Ning; Li, Sijie; Han, Rongrong; Huang, Qingjian; Hu, Jiangnan; Jin, Kunlin; Ji, Xunming; 0000-0002-1336-348X (Jin, Kunlin) (JKL International, 2018-10-01)
    Intracranial and extracranial arterial stenosis, the primary cause of chronic cerebral hypoperfusion (CCH), is a critical reason for the pathogenesis of vascular dementia and Alzheimer's disease characterized by cognitive ...

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