Browsing 2019 by Title
Now showing items 168-187 of 302
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Ladd’s Band Obstruction in 61 Year Old Physician
(2019-03-05)Ladd’s Band obstruction and congenital malrotation of the intestines is a rather uncommon anomaly with an incidence of 1 in 500 births and with symptomatic cases only appearing in 1 out of every 6000 births [1], [2]. ... -
Lance-Adams Syndrome: A Case Study
(2019-03-05)Abstract Background: Lance-Adams syndrome (LAS) is a rare condition caused by brain hypoxia commonly due to respiratory arrest leading to chronic uncontrollable myoclonus. The myoclonus usually develops weeks to months ... -
Late Night Social Networking Use and the Associations with Adolescent and Young Adult Sleep Quality, Substance Use, and Anxiety
(2019-03-05)Purpose: Research has shown social networking site use to be associated with adolescent and young adult health and risk behavior generally, but less is known about whether late night use is related to health and well-being. ... -
Lipoprotein Based Targeted Therapy for AML
(2019-03-05)Background: Acute myeloid leukemia (AML) is the most common acute leukemia in adults; it is only cured in less than 50% of the patients that are diagnosed with the disease. A new approach to the AML treatment is proposed ... -
Long Term Survival in Pediatric Renal Cell Carcinoma despite multiple relapses: A Case Study
(2019-03-05)Background Although common in adults, renal cell carcinoma (RCC) is extremely rare in pediatric populations, comprising of less than 5% of malignant renal tumors. Literature on the topic is scarce, and there currently is ... -
Making the Patient Safety Connection Between Rx and OTC: Assessment of an Active Learning Activity
(2019-03-05)Purpose: This active learning activity exercise allows the student to: Use available resources to learn information about prescription (Rx) and over-the-counter (OTC) medications Connect OTC product concerns with ... -
Mapping the binding site mediating carisoprodol’s direct activation of GABAA receptors
(2019-03-05)Carisoprodol (CSP) is a centrally-acting prescription muscle relaxant that can directly activate and allosterically modulate the GABAA receptor. GABAA receptors are the target of many different clinically prescribed ... -
Massive Intracranial Hemorrhage with Subsequent Subfalcine and Transtentorial Herniation: A Case Study
(2019-03-05)Background: Brain herniation is a progression of pathology due to increased intracranial pressure creating a mass effect. The mass effect created by a large intracranial hemorrhage on one side of the brain often leads to ... -
McLennan County Mosquito Research: Diversity and Disease-Vector Potential
(2019-03-05)Abstract Purpose: A multitude of vector-obligate diseases are increasingly becoming a greater importance to the United States of America. As climate change generates novel weather patterns, vector-mosquito ranges are ... -
Mechanisms Underlying Membrane Androgen Receptor-Induced Neurodegeneration
(2019-03-05)Purpose: A common characteristic of several neurodegenerative disorders is oxidative stress (OS). Many neurodegenerative disorders are more prevalent in men and postmenopausal women. Our lab has shown testosterone via a ... -
Medial periarticular clavicle fracture repair using inverted distal clavicle plate and sternal fixation: a case study
(2019-03-05)Background: Fractures of the medial third of the clavicle are rare, comprising less than 3% of all clavicle fractures. Available studies regarding medial clavicle fractures report frequent poor outcomes with traditionally-accepted ... -
Metformin Enhanced HIV Gene Expression and Production
(2019-03-05)Purpose: HIV-1 adopts several factors of host machinery to generate a permissive environment for viral replication and transmission. HIV-1 enhances the activity of mTORC1 which appears to be necessary for the optimal ... -
Metformin inhibits medulloblastoma cell growth and increases sensitivity to chemotherapy drugs
(2019-03-05)Purpose: Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Standard treatment is chemotherapy and radiation, both of which can be associated with long-term toxicity for pediatric patients. This project ... -
Microbial Natural Product Drug Discovery Through Systematic Sampling of Diverse Texas Soils
(2019-03-05)Purpose: Microorganisms have long been a valuable source of new pharmaceutically relevant small molecules. Because of their intrinsic need to compete for scarce resources in their microenvironment, they have often adapted ... -
Mito-nuclear compatibility in risk for cognitive decline in admixed populations
(2019-03-05)Background. The issue of missing heritability has vexed the study of many complex diseases, Alzheimer’s disease (AD) not excluded. Only ~35% of the heritability of AD has been accounted for, the majority of which lies in ... -
Mitochondrial oxidative stress and extrusion of mitochondrial DNA from endothelial cells: implications for maternal endothelial dysfunction in preeclampsia
(2019-03-05)Purpose: Preeclampsia is one of the leading causes of maternal mortality during pregnancy and a risk factor of cardiovascular disease for the mother later in life. Hypertension and endothelial dysfunction are common ... -
Mitochondrial RNA Sequencing Variation in Age-Related Pathologies
(2019-03-05)Background. Mitochondrial function has been implicated in a number of age-related disease pathologies, and post-transcriptional sequence modifications in mitochondrial RNA (mtRNA) have been correlated with variation in the ... -
MOG-specific Treg generation is potentially affected by thymic atrophy
(2019-03-05)Purpose: Increased chronic inflammation in the elderly is partially attributed to the disruption of central immune tolerance, comprising thymocyte negative selection and regulatory T cell (Treg) generation due to age-related ... -
Neuroprotective properties of sigma-1 Receptor in Retinal Ganglion cells from Optic Crush Model
(2019-03-05)Glaucoma is a group of neurodegenerative disorders that lead to the death of the retinal ganglion cells (RGC), optic nerve damage, and may ultimately cause blindness. Elevated intraocular pressure (IOP) is one of the major ... -
Neutrophils are more effective than monocytes at containment and clearance of Listeria monocytogenes
(2019-03-05)Neutrophils and monocytes are phagocytic cells that have previously been shown to be important for host protection during infection with the intracellular bacteria, Listeria monocytogenes. Previous studies have shown that ...