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Mitochondrial RNA Sequencing Variation in Age-Related Pathologies
Background. Mitochondrial function has been implicated in a number of age-related disease pathologies, and post-transcriptional sequence modifications in mitochondrial RNA (mtRNA) have been correlated with variation in the ...
Mito-nuclear compatibility in risk for cognitive decline in admixed populations
Background. The issue of missing heritability has vexed the study of many complex diseases, Alzheimer’s disease (AD) not excluded. Only ~35% of the heritability of AD has been accounted for, the majority of which lies in ...