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Recent Submissions
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Association between GDF5 single nucleotide polymorphism rs143383 and chronic lower back pain
(2019-03-05)Introduction. Low back pain presents a unique and ongoing challenge for patients and physicians. Of those who experience an episode of low back pain, 10% go on to develop persistent chronic low back pain (CLBP). However, ... -
Effects of Practicing Osteopathic Manipulative Treatment (OMT) on Hand Function
(2019-03-05)Purpose: Practitioners who use osteopathic manipulative treatment (OMT) rely on their hands to diagnose and treat patients. While the general population’s hand functionality declines with age, OMT practitioners seem to ... -
Effect of Palpatory Neuromodulation of the Trigeminal Nerve for Tenderness in the Posterior Neck Musculature
(2019-03-05)Purpose: The trigeminal nerve coordinates several reflexes in the head, including a head-retraction reflex (HRR) when a stimulus comes close to the face. HRR utilizes the posterior neck musculature (PNM) to remove the face ... -
Proximal Hamstring Tendinopathy Secondary to Malalignment Syndrome and the Effects of Running on Cross-Sloped Surfaces: A Case Report
(2019-03-05)Background Patients with proximal hamstring tendinopathy (PHT) will typically report deep buttock or thigh pain that increases with running speed which may also flare with prolonged sitting. Malalignment refers to a minimal ... -
Osteopathic Manipulation for Genital Pain - A Case Report
(2019-03-05)Abstract Background: For U.S. Osteopathic Manual Medicine (OMT) physicians, there is an over emphasis on medication, rather than the usage of manual diagnosis and therapy. We report a rare case of idiopathic penile pain ... -
Association of ABCB1 (rs1045642) single nucleotide polymorphism and drug metabolism reserve index (DMRI) with pain intensity among adults with chronic low back pain
(2019-03-05)Purpose Low back pain is the leading cause of disability in the United States. It is often associated with long term opioid use, which may lead to opioid misuse and serious adverse events. Current clinical guidelines caution ... -
Complex Regional Pain Syndrome Presenting Similar to A Myocardial Infarction: A Case Study
(2019-03-05)Background: Complex Regional Pain Syndrome (CRPS) is a disease of chronic pain often times arising after an initial triggering event (i.e., surgery, trauma, stroke etc.) that is refractory to normal pain management. CRPS ... -
Osteopathic Manipulative Treatments to Improve Functionality of Parkinson’s Disease: Case Study
(2019-03-05)Background: Parkinson’s is a progressive neurodegenerative disease, second most common neurodegenerative disease. Standard of care is generally pharmacologic treatment with Levodopa, as it manages the bradykinesias, tremors ... -
Chemical Reprogramming of Mouse and Human Müller glia into Retinal Ganglion-Like Cells (RGCs)
(2019-03-05)Chemical Reprogramming of Mouse and Human Müller glia into Retinal Ganglion-Like Cells (RGCs) Yan Fan, Wei Zhang, Sai Chavala Department of Pharmacology and Neuroscience, Graduate School of Biomedical Sciences, UNT Health ... -
Inhibition of Mitochondrial Respiratory Chain Complex I Induces Vascular Endothelial Cell Apoptosis and Release of Mitochondrial DNA
(2019-03-05)Purpose: Vascular endothelial oxidative stress is a common feature of preeclampsia, a pregnancy specific hypertensive syndrome with high incidence of maternal and fetal mortality and morbidity. Cellular oxidative stress ... -
Store-Operated Calcium Entry in Mesangial Cells And Glomerular Inflammatory Responses: Role of Interleukin-6
(2019-03-05)Purpose: Emerging evidence indicates that immunological and inflammatory mechanisms play a significant role in the development of diabetic nephropathy (DN). The early features of DN include accumulation of extracellular ... -
Poly lactic-co-glycolic acid (PLGA) mediated gene delivery to astrocytes requires arginine-modified polyethylenimine (PEI) polymer to facilitate gene expression
(2019-03-05)Purpose: The global burden of neurodegenerative diseases and disorders devastate not only their victims but also their loved ones. Astrocyte dysfunction is a hallmark of central nervous system injury or infection. As a ... -
Qualitative Analysis of the Reasons People with Spinal Cord Injury Opt to Enroll in an Exercise Program and their Barriers to Participation
(2019-03-05)Objective: Understand why people with spinal cord injury (SCI) enrolled in an online exercise trial, what barriers to exercise they cited, and their plans to address these barriers. Design: Qualitative study of participant ... -
Does High Intensity Aerobic Exercise Improve Postural Control for Older Adults?
(2019-03-05)Purpose: While falls are a major source of disability in the aging population, walking has been linked to reduced risk of falls for older adults1-2. Treadmill walking has even been shown to positively impact muscle-strengthening, ... -
Soft Robotic Glove for Post-Stroke/Cerebral Palsy Hand Rehabilitation
(2019-03-05)Soft Robotic Glove for Post-Stroke/Cerebral Palsy Hand Rehabilitation Jacob Robinson, UNTHSC OMS-II; Rita Paterson, PHD UNTHSC Objective: The upper extremity plays a vital role in manipulation, communication and overall ... -
Treatment of hyperbaric oxygen combine with cannabidiol promote recovery of brain damage in newborn rats with hypoxia-ischemia
(2019-03-05)Objective: Hypoxic-ischemic (HI) encephalopathy is a severe disease seen commonly in clinical settings. However, there is a limited body of work on effective therapies to repair HI brain damage. To test the potential ... -
Effect of Enhanced External Counter pulsation on Exercise Endurance of Different Populations
(2019-03-05)Abstract Background and Purpose: Enhanced external counter pulsation (EECP)is a beneficial adjunct therapy used widely according to Cardiac rehabilitation guideline. However, the relationship between EECP and exercise ... -
The Effect of Exercise Programs on Children with Autism Spectrum Disorder (ASD): A Review of Current Literature
(2019-03-05)Purpose Autism Spectrum Disorder (ASD) is characterized by challenges with social skills and delays in motor skills (Bremer, Balogh, & Lloyd, 2014; Caçola et al., 2019). Children with ASD tend to have a greater need for ... -
Soft Robotic Exoskeleton for Cerebral Palsy Rehabilitation
(2019-03-05)Purpose: This work presents development of a soft robotic exoskeleton to provide active and passive therapeutic-assistive hand motion for children between the ages of 5-12 suffering from Cerebral Palsy (CP) while recording ... -
Hand Force Measurement Using A Human-Powered Linear Movement
(2019-03-05)Abstract Background: Cerebral Palsy (CP) is a neurological disorder that affects many motor functions, such as muscle tone. 60-80% of children born with CP neurological movement disorders have functional limitations in the ...