Purpose: The purpose of the present study was to identify mitochondrial proteins that undergo changes in cysteine sulfenation during aging. Methods: Studies were conducted in rats when they were 5 or 30 months of age. ...

Background: As the United States population continues to age, more people will be diagnosed with Alzheimer’s Disease (AD) and dementia. Along with this increase in diagnosis comes an increase in the need for people to serve ...

Purpose: Interprofessional collaboration is essential in geriatric healthcare settings due to the complex needs of older adults. The University of North Texas Health Science Center and Texas Christian University’s Harris ...

Purpose: Presenilin-1 (PS1) protein is the catalytic subunit of the γ-secretase complex, and participates in the processing of β-amyloid precursor protein (APP) to produce Aβ peptide and Notch 1 receptor to release Notch ...

1 Purpose Cardiovascular disease (CVD) is a leading cause of mortality in the United States, and age alone is a risk factor for developing CVD1. Regular aerobic exercise can help prevent arterial stiffening that occurs ...

Purpose: Although intermittent hypoxic training (IHT) has proven effective against various clinical disorders, its impact on mild cognitive impairment (MCI) is unknown. This study was to test if IHT was safe as a novel ...

Hypothesis/Objective Recruiting older adults into research is a complex task and utilizing ineffective recruitment methods is a waste of research grant money and researcher time. Research in aging and Alzheimer’s disease ...

Purpose: A common characteristic of several neurodegenerative disorders is oxidative stress (OS). Many neurodegenerative disorders are more prevalent in men and postmenopausal women. Our lab has shown testosterone via a ...

Purpose Aging is associated with a decrease in brain function and vitality, along with an increased risk to stressors. Oxidative stress is a mechanism associated with aging, in which antioxidant defenses are overcome by ...

Purpose A rapidly aging demographic, aged 65 and older, is expected to double by 2060 reaching 98 million and creating demands for better healthcare. While the number of co-occurring diseases increase in the aging population, ...