Immunology
Browse by
Recent Submissions
-
The Effect of Lymph Isolated during Osteopathic Lymphatic Pump Treatment on the Immune Response against Acute Pneumonia
(2019-03-05)Purpose: Community acquired pneumonia (CAP) accounts for over 1,000,000 hospital admissions yearly. Osteopathic physicians use lymphatic pump techniques (LPT) as a tool to mobilize lymph and treat infectious disease, such ... -
MOG-specific Treg generation is potentially affected by thymic atrophy
(2019-03-05)Purpose: Increased chronic inflammation in the elderly is partially attributed to the disruption of central immune tolerance, comprising thymocyte negative selection and regulatory T cell (Treg) generation due to age-related ... -
Chemotherapeutic drugs increase CS1 (CD319) expression on multiple myeloma cells enhancing NK cell mediated killing
(2019-03-05)Background: Multiple myeloma (MM) is characterized by malignant plasma cells. The clinical diagnosis includes end-organ damage, such as hypercalcemia and renal insufficiency. CS1, a member of the Signaling Lymphocyte ... -
Surface PCNA enables pancreatic and colon cancer stem cells to inhibit NK cell effector function
(2019-03-05)Purpose: Cancer stem cells (CSC) are a subset of tumor cells that have a stem-cell-like phenotype and are thought to facilitate metastasis by evading peripheral NK cell effector function. NK cell function is regulated by ... -
Conceptualizing Stress as a Mediator of Lung Microbiota’s Influence on Respiratory Health
(2019-03-05)Purpose: Stress responses have been shown to alter the microbial ecosystem along the respiratory tract affecting the elimination and migration of microbes. However, to date little is known about the mechanisms through which ... -
Radiation-mediated effect on exosomal and non-exosomal-derived microRNA-21 (miR21) gene expression by Triple Negative Breast Cancer cell line MDA-MB-231
(2019-03-05)Background: Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype which lacks estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor-2 receptor (HER2). TNBC is therefore ... -
Neutrophils are more effective than monocytes at containment and clearance of Listeria monocytogenes
(2019-03-05)Neutrophils and monocytes are phagocytic cells that have previously been shown to be important for host protection during infection with the intracellular bacteria, Listeria monocytogenes. Previous studies have shown that ... -
Atrophied thymus creates tTreg repertoire holes diminishing an antigen-specific population in the periphery
(2019-03-05)Purpose: We have shown that there is an increased ratio of total thymic T regulatory (tTreg) cells to thymic T conventional (tTcon) cells generated by the atrophied thymus related to aging. This observation, coupled with ...
RSS 1.0