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A Systematic Review of the Utility of Procalcitonin in Bacterial Meningitis
Purpose/Objective: To review the utility of procalcitonin (PCT) in the management of bacterial meningitis (BM). Methods: An English-language MEDLINE search from 1964 through June 20, 2018 was completed using the following ...
The HIV-1 negative regulatory factor (Nef) is important for efficient virus production from astrocytes
The HIV-1 negative regulatory factor (Nef) is important for efficient virus production from astrocytes Suresh Kandel, MS and Johnny J. He, PhD Email: Johnny.He@unthsc.edu; Suresh.firstname.lastname@example.org Department of Microbiology, ...
Impairment of HIV-1 replication by UBE3A- and HIV-1 Nef-mediated regulation of proteasomal degradation.
To date, regulation of HIV-1 life cycle has been mainly explained by the stage-specific expression of HIV-1 viral genes, even if elimination processes of the synthesized proteins after completion of their duties in the ...
Metformin Enhanced HIV Gene Expression and Production
Purpose: HIV-1 adopts several factors of host machinery to generate a permissive environment for viral replication and transmission. HIV-1 enhances the activity of mTORC1 which appears to be necessary for the optimal ...