HSC College of Pharmacy
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The HSC College of Pharmacy is committed to developing patient-centric pharmacy professionals trained in an interprofessional environment. We advocate a team health care environment coupled with optimizing health through discovery.
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Recent Submissions
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The Association of Multimorbidity With Whole Health Activities Among Adults in the United States: Evidence From the NHIS and BRFSS
(Academic Consortium for Integrative Medicine & Health, 2023-05-08)BACKGROUND: Whole health is a holistic approach encompassing integrative medicine, emotional, and spiritual health and is critical to improving health outcomes among individuals with multimorbidity. OBJECTIVE: To examine ... -
Collagen Crosslinking for Keratoconus: Cellular Signaling Mechanisms
(MDPI, 2023-05-16)Collagen crosslinking (CXL) is a widely used treatment to halt the progression of keratoconus (KC). Unfortunately, a significant number of patients with progressive KC will not qualify for CXL, including those with corneas ... -
Association of multimorbidity with the use of health information technology
(Sage Publications, 2023-05-01)OBJECTIVE: To examine the association of multimorbidity with health information technology use among adults in the USA. METHODS: We used cross-sectional study design and data from the Health Information National Trends ... -
Unravelling the Impact of Cyclic Mechanical Stretch in Keratoconus-A Transcriptomic Profiling Study
(MDPI, 2023-04-28)Biomechanical and molecular stresses may contribute to the pathogenesis of keratoconus (KC). We aimed to profile the transcriptomic changes in healthy primary human corneal (HCF) and KC-derived cells (HKC) combined with ... -
Renal-Protective Roles of Lipoic Acid in Kidney Disease
(MDPI, 2023-04-14)The kidney is a crucial organ that eliminates metabolic waste and reabsorbs nutritious elements. It also participates in the regulation of blood pressure, maintenance of electrolyte balance and blood pH homeostasis, as ... -
Increase in body mass index during the COVID-19 pandemic among people who smoke: An analysis of multi-site electronic health records
(PLOS, 2023-04-12)The effects of the COVID-19 period among people who smoke (compared by sex) are largely unknown. The purpose of this study was to compare body mass index (BMI) increase among men and women who smoked during the pandemic. ... -
Salivary Exosomes in Health and Disease: Future Prospects in the Eye
(MDPI, 2023-04-14)Exosomes are a group of vesicles that package and transport DNA, RNA, proteins, and lipids to recipient cells. They can be derived from blood, saliva, urine, and/or other biological tissues. Their impact on several diseases, ... -
Long-term intermittent fasting improves neurological function by promoting angiogenesis after cerebral ischemia via growth differentiation factor 11 signaling activation
(PLOS, 2023-03-31)Intermittent fasting (IF), an alternative to caloric restriction, is a form of time restricted eating. IF conditioning has been suggested to have neuroprotective effects and potential long-term brain health benefits. But ... -
Competitive Displacement Restores the Hyperpolarized (15)N NMR Signal in Blood Plasma
(American Chemical Society, 2023-03-28)Hyperpolarized (HP) NMR can improve the sensitivity of conventional NMR experiments by several orders of magnitude, thereby making it feasible to detect the signal of low sensitivity nuclei such as (13)C and (15)N nuclei ... -
Peroxisome proliferator-activated receptor-alpha (PPARalpha) regulates wound healing and mitochondrial metabolism in the cornea
(National Academy of Science, 2023-03-22)Diabetes can result in impaired corneal wound healing. Mitochondrial dysfunction plays an important role in diabetic complications. However, the regulation of mitochondria function in the diabetic cornea and its impacts ... -
A Multi-Level Analysis of Individual and Neighborhood Factors Associated with Patient Portal Use among Adult Emergency Department Patients with Multimorbidity
(MDPI, 2023-01-22)BACKGROUND: Patient portals tethered to electronic health records (EHR) have become vital to patient engagement and better disease management, specifically among adults with multimorbidity. We determined individual and ... -
Does Team Based Learning (TBL) in the Pharmacy Classroom Foster Leadership Skills in the Workplace?
(University of Minnesota Department of Pharmaceutical Care & Health Systems, 2023-01-12)Objective: A well-functioning healthcare team is important to optimizing the health outcomes of patients. As such, the use of Team Based Learning (TBL) in the education of health professionals has emerged as one of the ... -
A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage
(Frontiers Media S.A., 2022-11-18)Growing evidence links oxidative stress to the development of a cataract and other diseases of the eye. Treatments for lens-derived diseases are still elusive outside of the standard surgical interventions, which still ... -
Leading Predictors of COVID-19-Related Poor Mental Health in Adult Asian Indians: An Application of Extreme Gradient Boosting and Shapley Additive Explanations
(MDPI, 2023-01-09)During the COVID-19 pandemic, an increase in poor mental health among Asian Indians was observed in the United States. However, the leading predictors of poor mental health during the COVID-19 pandemic in Asian Indians ... -
Factors associated with COVID-19-related mental health among Asian Indians in the United States
(Elsevier B.V., 2023-01-11)BACKGROUND: In the United States, the COVID-19 pandemic has caused increased mental health symptoms and mental illness. Specific subgroups such as Asian Indians in the US have also been subject to additional stressors due ... -
The Underlying Relationship between Keratoconus and Down Syndrome
(MDPI, 2022-09-24)Keratoconus (KC) is one of the most significant corneal disorders worldwide, characterized by the progressive thinning and cone-shaped protrusion of the cornea, which can lead to severe visual impairment. The prevalence ... -
Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model
(MDPI, 2022-09-24)The purpose of this study was to investigate the role of sphingosine kinase 1 (SphK1), which generates sphingosine-1-phosphate (S1P), in corneal neovascularization (NV). Wild-type (WT) and Sphk1 knockout (Sphk1(-/-)) mice ... -
Destabilizing COXIV in Muller Glia Increases Retinal Glycolysis and Alters Scotopic Electroretinogram
(MDPI, 2022-12-12)Muller glia (MG), the principal glial cell of the retina, have a metabolism that defies categorization into glycolytic versus oxidative. We showed that MG mount a strong hypoxia response to ocular hypertension, raising the ... -
Latest in Cellular Pathology Research
(MDPI, 2022-12-24)The year 2021 marked the 10th anniversary of the publication of Cells. To celebrate this milestone, a Special Issue entitled "10th Anniversary of Cells—Advances in Cellular Pathology" was launched. The goal of this Special ... -
Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm
(PLOS, 2020-06-11)Metformin, an anti-diabetes drug, has been recently emerging as a potential "anti-aging" intervention based on its reported beneficial actions against aging in preclinical studies. Nonetheless, very few metformin studies ...
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