Epidemiology of Cholera in Malawi, 2002-2003

Nkhoma, Ella, Epidemiology of Cholera in Malawi, 2002-2003. Master of Public Health (Epidemiology), August 2004, 33pp., 4 tables, 3 figures, bibliography, 24 titles. The objective of the present study was to characterize epidemic cholera in Malawi from 2002-2003. National and district-level surveillance records were used for the analyses in this study. The study employed Poisson regression, log-linear analysis, epidemic curve analysis, curve-fitting procedures and epidemic model simulations. District-level determinants of cholera mortality included various sociodemographic indicators. Significant two-way interactions were observed for age and district, with the oldest age group (65+) experiencing the highest risk of symptomatic cholera and residents of Nkhatabay districts also experiencing the most increased risk. Temporal analysis revealed the existence of secondary outbreaks and demonstrated the contribution of preexisting immunity to epidemic dynamics.