Review of the History of Coronary Stenting, Role and Evolution of Adjunctive Pharmacotherapy and Experience with an Ongoing Drug-Eluting Stent Trial
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Kang, Mi Jung. Review of the History of Coronary Stenting, Role and Evolution of Adjunctive Pharmacotherapy and Experience with an Ongoing Drug-Eluting Stent Trial. Master of Science (Clinical Research Management), December 2005, 116 pp., 6 tables, 12 figures, bibliography, 61 titles. The history of stent development with regard to the use of coating materials and eluting drugs, with special emphasis on mechanism of release and duration of action of drugs used in drug-eluting stents, was summarized. The general safety profile of currently used adjunctive pharmacotherapy to coronary stenting, with special emphasis on the clinical trials providing the scientific assessments of the effectiveness and safety of the regimens was reviewed. The enrollment process and the critical role of the Clinical Research Coordinator (CDC) in the process of the implementation of a clinical study with a new drug-eluting stent were described.
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Cardiovascular System
Laboratory and Basic Science Research
Life Sciences
Medicinal Chemistry and Pharmaceutics
Medicine and Health Sciences
Other Pharmacy and Pharmaceutical Sciences
Pharmaceutical Preparations
Pharmacology
Pharmacy and Pharmaceutical Sciences
Surgery
History
coronary stenting
adjunctive pharmacotherapy
drug-eluting stent trial
Clinical Research Coordinator
safety
effectiveness
clinical study