Associate Professor, Microbiology, Immunology & Genetics

Email: Michael.Allen@unthsc.edu

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Recent Submissions

  • Genetically engineered probiotic for the treatment of phenylketonuria (PKU); assessment of a novel treatment in vitro and in the PAHenu2 mouse model of PKU 

    Durrer, Katherine E.; Allen, Michael S.; Hunt von Herbing, Ione; 0000-0003-2293-8078 (Allen, Michael S.) (PLOS, 2017-05-17)
    Phenylketonuria (PKU) is a genetic disease characterized by the inability to convert dietary phenylalanine to tyrosine by phenylalanine hydroxylase. Given the importance of gut microbes in digestion, a genetically engineered ...
  • Genome Sequence of a Proteus mirabilis Strain Isolated from the Salivary Glands of Larval Lucilia sericata 

    Yuan, Ye; Zhang, Yu; Fu, Shuhua; Crippen, Tawni L.; Visi, David K.; Benbow, M. Eric; Allen, Michael S.; Tomberlin, Jeffrey K.; Sze, Sing-Hoi; Tarone, Aaron M.; 0000-0003-2293-8078 (Allen, Michael S.) (American Society for Microbiology, 2016-07-28)
    We announce a draft genome sequence of a Proteus mirabilis strain derived from Lucilia sericata salivary glands. This strain is demonstrated to attract and induce oviposition by L. sericata, a common blow fly important to ...
  • Hurricane Harvey Impacts on Water Quality and Microbial Communities in Houston, TX Waterbodies 

    LaMontagne, Michael G.; Zhang, Yan; Guillen, George J.; Gentry, Terry J.; Allen, Michael S.; 0000-0003-2293-8078 (Allen, Michael S.); 0000-0001-5784-4659 (Zhang, Yan) (Frontiers Media S.A., 2022-06-14)
    Extreme weather events can temporarily alter the structure of coastal systems and generate floodwaters that are contaminated with fecal indicator bacteria (FIB); however, every coastal system is unique, so identification ...
  • Genome Sequence of a Providencia stuartii Strain Isolated from Luciliasericata Salivary Glands 

    Yuan, Ye; Zhang, Yu; Fu, Shuhua; Crippen, Tawni L.; Visi, David K.; Benbow, M. Eric; Allen, Michael S.; Tomberlin, Jeffrey K.; Sze, Sing-Hoi; Tarone, Aaron M.; 0000-0003-2293-8078 (Allen, Michael S.) (American Society for Microbiology, 2017-04-27)
    We present here the draft genome sequence of a Providencia stuartii strain, derived from the salivary glands of larval Lucilia sericata, a common blow fly important to forensic, medical, and veterinary science. The genome ...
  • Effects of temperature on bacterial microbiome composition in Ixodes scapularis ticks 

    Thapa, Santosh; Zhang, Yan; Allen, Michael S.; 0000-0003-2293-8078 (Allen, Michael S.); 0000-0001-5784-4659 (Zhang, Yan) (John Wiley & Sons, Inc., 2018-09-21)
    Ixodes scapularis, the blacklegged deer tick, is the principal vector of Lyme disease in North America. Environmental factors are known to influence regional and seasonal incidence of Lyme disease and possibly the endemicity ...
  • The Adult Phenylketonuria (PKU) Gut Microbiome 

    Mancilla, Viviana J.; Mann, Allison E.; Zhang, Yan; Allen, Michael S.; 0000-0003-2293-8078 (Allen, Michael S.); 0000-0001-5784-4659 (Zhang, Yan) (MDPI, 2021-03-04)
    Phenylketonuria (PKU) is an inborn error of phenylalanine metabolism primarily treated through a phenylalanine-restrictive diet that is frequently supplemented with an amino acid formula to maintain proper nutrition. Little ...
  • Bacterial microbiomes of Ixodes scapularis ticks collected from Massachusetts and Texas, USA 

    Thapa, Santosh; Zhang, Yan; Allen, Michael S.; 0000-0003-2293-8078 (Allen, Michael S.); 0000-0001-5784-4659 (Zhang, Yan) (BioMed Central Ltd., 2019-06-24)
    BACKGROUND: The blacklegged tick, Ixodes scapularis, is the primary vector of the Lyme disease spirochete Borrelia burgdorferi in North America. Though the tick is found across the eastern United States, Lyme disease is ...
  • Common Lung Microbiome Identified among Mechanically Ventilated Surgical Patients 

    Smith, Ashley D.; Zhang, Yan; Barber, Robert C.; Minshall, Christian T.; Huebinger, Ryan M.; Allen, Michael S.; 0000-0003-2293-8078 (Allen, Michael S.); 0000-0001-5784-4659 (Zhang, Yan); 0000-0001-6857-0286 (Barber, Robert C.) (PLOS, 2016-11-29)
    The examination of the pulmonary microbiome in patients with non-chronic disease states has not been extensively examined. Traditional culture based screening methods are often unable to identify bacteria from bronchoalveolar ...
  • Comparison of the Bacterial Gut Microbiome of North American Triatoma spp. With and Without Trypanosoma cruzi 

    Mann, Allison E.; Mitchell, Elizabeth A.; Zhang, Yan; Curtis-Robles, Rachel; Thapa, Santosh; Hamer, Sarah A.; Allen, Michael S.; 0000-0003-2293-8078 (Allen, Michael S.); 0000-0001-5784-4659 (Zhang, Yan) (Frontiers Media S.A., 2020-03-13)
    Chagas disease, caused by the hemoflagellate protist Trypanosoma cruzi, affects nearly 6 million people worldwide, mainly in Latin America. Hematophagous triatomine insects ("kissing bugs") are the primary vectors of T. ...
  • Variations of the lung microbiome and immune response in mechanically ventilated surgical patients 

    Huebinger, Ryan M.; Smith, Ashley D.; Zhang, Yan; Monson, Nancy L.; Ireland, Sara J.; Barber, Robert C.; Kubasiak, John C.; Minshall, Christian T.; Minei, Joseph P.; Wolf, Steven E.; Allen, Michael S.; 0000-0001-6857-0286 (Barber, Robert C.); 0000-0001-6857-0286 (Allen, Michael S.) (PLOS, 2018-10-24)
    Mechanically ventilated surgical patients have a variety of bacterial flora that are often undetectable by traditional culture methods. The source of infection in many of these patients remains unclear. To address this ...