Age-related Impairment of Vascular Structure and Functions

Date

2017-10-01

Authors

Xu, Xianglai
Wang, Brian
Ren, Changhong
Hu, Jiangnan
Greenberg, David A.
Chen, Tianxiang
Xie, Liping
Jin, Kunlin

ORCID

0000-0002-1336-348X (Jin, Kunlin)

Journal Title

Journal ISSN

Volume Title

Publisher

JKL International

Abstract

Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.

Description

Citation

Xu, X., Wang, B., Ren, C., Hu, J., Greenberg, D. A., Chen, T., Xie, L., & Jin, K. (2017). Age-related Impairment of Vascular Structure and Functions. Aging and disease, 8(5), 590-610. https://doi.org/10.14336/AD.2017.0430