COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?

Files

10.14336_AD.2020.0402.pdf (725.61 KB)

Date

2020-05-09

Authors

Chakrabarti, Sankha Shubhra
Kaur, Upinder
Banerjee, Anindita
Ganguly, Upsana
Banerjee, Tuhina
Saha, Sarama
Parashar, Gaurav
Prasad, Suvarna
Chakrabarti, Suddhachitta
Mittal, Amit

ORCID

0000-0002-1336-348X (Jin, Kunlin)

Journal Title

Journal ISSN

Volume Title

Publisher

JKL International

Abstract

The ongoing Corona virus (COVID-19) pandemic has witnessed global political responses of unimaginable proportions. Many nations have implemented lockdowns that involve mandating citizens not to leave their residences for non-essential work. The Indian government has taken appropriate and commendable steps to curtail the community spread of COVID-19. While this may be extremely beneficial, this perspective discusses the other reasons why COVID-19 may have a lesser impact on India. We analyze the current pattern of SARS-CoV-2 transmission, testing, and mortality in India with an emphasis on the importance of mortality as a marker of the clinical relevance of COVID-19 disease. We also analyze the environmental and biological factors which may lessen the impact of COVID-19 in India. The importance of cross-immunity, innate immune responses, ACE polymorphism, and viral genetic mutations are discussed.

Description

Keywords

Ace2, Covid-19, India, cross-immunity, mortality, transmission

Citation

Chakrabarti, S. S., Kaur, U., Banerjee, A., Ganguly, U., Banerjee, T., Saha, S., Parashar, G., Prasad, S., Chakrabarti, S., Mittal, A., Agrawal, B. K., Rawal, R. K., Zhao, R. C., Gambhir, I. S., Khanna, R., Shetty, A. K., Jin, K., & Chakrabarti, S. (2020). COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?. Aging and disease, 11(3), 480-488. https://doi.org/10.14336/AD.2020.0402

URI

https://hdl.handle.net/20.500.12503/31690

Collections

Publications -- Kunlin Jin