The Validation of the RapidHIT ID System for Human Identification

dc.contributor.advisorBudowle, Bruce
dc.contributor.committeeMemberCihlar, Jennifer C.
dc.contributor.committeeMemberGwirtz, Patricia A.
dc.creatorCampos, Gemma R.
dc.creator.orcid0000-0003-4743-6672 (Campos, Gemma R. )
dc.date.accessioned2020-04-22T19:28:53Z
dc.date.available2020-04-22T19:28:53Z
dc.date.issued2020-05
dc.description.abstractForensic scientists routinely employ short tandem repeat (STR) typing as a means to identify or exclude individuals as the donors of biological evidence at crime scenes. Despite developments in automation of STR typing workflow, this time-consuming work requires the expertise and resources of a dedicated forensic genetics laboratory. Rapid DNA technology, a fully automated, turnkey system, offers a simple, 90-minute swab-to-profile approach to generate STR profiles, requiring minimal training and expertise to operate the system. As Rapid DNA continues to be developed and implemented, validation studies are necessary to ensure the quality of analyses performed by Rapid DNA instruments. A series of studies in accordance with SWGDAM guidelines were designed to test different performance measures of the RapidHIT ID System for Human Identification (Thermo Fisher Scientific). The results from this study provide opportunities for protocol and user guide revisions, software improvements, and highlight parts of instrumentation that can be improved for future models.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/29838
dc.language.isoen
dc.subjectRapid DNA
dc.subjectRapidHIT
dc.subjectSTR
dc.subject.meshForensic Genetics / methods
dc.subject.meshMicrosatellite Repeats
dc.subject.meshForensic Anthropology / methods
dc.subject.meshValidation Study
dc.subject.meshDNA / isolation & purification
dc.subject.meshDNA Fingerprinting / instrumentation
dc.titleThe Validation of the RapidHIT ID System for Human Identification
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineForensic Genetics
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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