Scott Stoll2019-08-222019-08-222006-05-012014-02-11https://hdl.handle.net/20.500.12503/29614Janice Thomas, D.O., M.S. Immediate Effects of Osteopathic Manipulative Treatments on Immune Function in a Healthy Population: A Pilot Study. Master of Science (Clinical Research and Education – OMM), May 2006, 75 pp, 3 tables, 5 figures, 66 references, 24 titles. Objectives: The purpose of this pilot study was to investigate the immediate effects of Osteopathic Manipulative Treatment (OMT) on immune function in a healthy population. Methods: This was a randomized, blinded and controlled clinical trial. 50 healthy individuals, ages 18 to 40, were recruited. Subjects were randomly assigned to one of two groups: OMT or Rest (control). Blood and saliva samples were collected pre and post-intervention (thirty minutes of OMT or Rest). Samples were analyzed for a CBC, salivary IgA, and various lymphocyte populations. Results: This study successfully demonstrated the feasibility of this protocol. No statistically significant differences in outcome measures were identified between the two groups, nor were any apparent trends identified. Conclusion: This study established a framework for future research investigating the effects OMT on acute and chronic infection, chronic pain, and immunocompromised populations in human and/or animal populations.application/pdfenAlternative and Complementary MedicineHemic and Immune SystemsImmune System DiseasesImmunityImmunology and Infectious DiseaseInvestigative TechniquesLife SciencesMedicine and Health SciencesOsteopathic Medicine and OsteopathyRehabilitation and TherapySomatic Bodywork and Related Therapeutic PracticesTherapeuticsImmediate effectsosteopathic manipulative treatmentsOMMimmune functionhealthy populationOMTThesis