Bens, Annita V.2019-08-222019-08-222005-12-012014-05-30https://hdl.handle.net/20.500.12503/27791Kang, Mi Jung. Review of the History of Coronary Stenting, Role and Evolution of Adjunctive Pharmacotherapy and Experience with an Ongoing Drug-Eluting Stent Trial. Master of Science (Clinical Research Management), December 2005, 116 pp., 6 tables, 12 figures, bibliography, 61 titles. The history of stent development with regard to the use of coating materials and eluting drugs, with special emphasis on mechanism of release and duration of action of drugs used in drug-eluting stents, was summarized. The general safety profile of currently used adjunctive pharmacotherapy to coronary stenting, with special emphasis on the clinical trials providing the scientific assessments of the effectiveness and safety of the regimens was reviewed. The enrollment process and the critical role of the Clinical Research Coordinator (CDC) in the process of the implementation of a clinical study with a new drug-eluting stent were described.application/pdfenCardiovascular DiseasesCardiovascular SystemLaboratory and Basic Science ResearchLife SciencesMedicinal Chemistry and PharmaceuticsMedicine and Health SciencesOther Pharmacy and Pharmaceutical SciencesPharmaceutical PreparationsPharmacologyPharmacy and Pharmaceutical SciencesSurgeryHistorycoronary stentingadjunctive pharmacotherapydrug-eluting stent trialClinical Research Coordinatorsafetyeffectivenessclinical studyProfessional Report