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UNTHSC Scholar is an open access repository of the intellectual output and publicly available materials of the university. UNTHSC Scholar provides stable access to data, highlights community partnerships and engagement, and enables discovery of these works by the international scientific community. It preserves the history, growth and innovation of the University of North Texas Health Science Center as an institution.
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The Role of Angiotensin Converting Enzyme 1 within the Median Preoptic Nucleus Following Chronic Intermittent Hypoxia (2016-08)These experiments focused on the importance of the brain renin-angiotensin system (RAS) in hypertension caused by a chronic intermittent hypoxia (CIH) model of the hypoxemia associated with sleep apnea. In the CIH model, ...
(2016-05)Fewer than 10% of the 360,000 people who suffer out-of-hospital cardiac arrest annually in the U.S. survive to hospital discharge. Many suffer brain injuries that greatly affect their daily activities and quality of life. ...
Positive allosteric modulation of alpha7 nicotinic acetylcholine receptors as a novel approach to treatment of ischemic stroke (2017-12)Ischemic cerebral stroke is a leading cause of disability and death worldwide. Despite substantial investments in developing anti-stroke medicines, clinically effective pharmacological treatments remain inadequate. Clinical ...
Creation of a biotechnology discovery platform for fighting the transmission of vector-borne infectious diseases (2017-08)Vector-borne diseases have become a global pandemic threatening 40% of the world's population with infectious diseases like malaria and Lyme disease becoming ever more of a concern. The best treatment of vector-borne ...