Browsing by Subject "COPD"
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Item Association Between Emergency Hospital Admissions of the Adult Population with Preexisting Respiratory Conditions and Ozone Air Quality Index(2006-12-01) Muzina, Miranda; Gratton, Terry; Mains, Doug A.; Sandhu, RaghbirMuzina, Miranda, Association Between Emergency Hospital Admissions of the Adult Population with Preexisting Respiratory Conditions and Ozone Air Quality Index. Master of Public Health (Environmental Health), December 2006, 117 pp., 23 tables, 18 figures, references, 128 titles. This study examined if an association exists between seasonal ozone air pollution in the Fort Worth area and patients admitted to local area hospitals with existing asthma, pneumonia, bronchitis and COPD. Ozone is secondary pollutant formed in a complex reaction between oxides of nitrogen and volatile organic compounds, in the presence of sunlight and heat. The EPA has classified the Dallas-Fort Worth area as a non-attainment area by for ozone. The study did not find any apparent association between seasonal ozone AQI and the emergency respiration admissions. The available hospital data significantly limited analyzing the connection between emergency hospitalization and daily fluctuations of ozone. Further studies are needed to address this complex relationship in a broader perspective.Item COPD Handout materials(2008-01-01)Item Does Osteopathic Manipulative Treatment Improve Dyspnea and Exercise Tolerance Subjects with Stable Chronic Obstructive Pulmonary Disease?(2006-05-01) Pickett, Carolyn M.; Stoll, Scott; Cruser, des Anges; Licciardone, John C.Pickett, Carolyn M., D.O., M.S. Does Osteopathic Manipulative Treatment Improve Dyspnea and Exercise Tolerance in Subjects with Stable Chronic Obstructive Pulmonary Disease? Master of Science (Clinical Research and Education – OMM), May 2006, 54 pages, 10 tables, 4 figures, references 48 titles. Chronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of death globally and is projected to increase. This highly prevalent and costly disease causes reduced physical and social functioning, and none of the existing medications for COPD seem to modify long-term decline in lung function. COPD patients with the severe dyspnea have more deficits in the health status and energy. Reduced functional status has been significantly correlated with health related quality of life. Osteopathic Manipulative Treatment (OMT) has been suggested for treatment of COPD as early as 1902, some research indicates that OMT may improve dyspnea and exercise tolerance, yet there are few published studies on OMT and COPD. Study goals were to increase scientific knowledge about how OMT may immediately improve dyspnea and exercise tolerance in stable COPD following exertion. This RCT was approved by the Institutional Review Board at the University of North Texas Health Science Center (UNTHSC) in Fort Worth and funded by the Osteopathic Research Center (ORC) at UNTHSC. –Hypothesis 1: A single intervention of OMT will improve dyspnea in a stable COPD subject, as measured by response to the Borg scale with exertion, when compared to no treatment. –Hypothesis: a single intervention of OMT will improve exercise tolerance in a stable COPD subject, as measured by distance walked during the six-minute walk test, when compared to no treatment. Twenty-one subjects completed the trial, 10 in the OMT group and 11 in the no-treatment group. No significant differences were found in the Borg scale or 6MWT following OMT. This study is limited by a small sample size and single OMT intervention design; however, it does demonstrate the feasibility of this research at this institution and may lead to a larger, more definitive and funded clinical trial.Item North Texas Health & Science - 2011, Issue 1(University of North Texas Health Science Center at Fort Worth, 2011-01-01)Item SURGICAL MANAGEMENT OF BASILAR BULLOUS EMPHYSEMA(2013-04-12) Simonsen, CameronPurpose: Emphysema is an abnormal enlargement of the air spaces distal to the terminal respiratory bronchioles. This enlargement is caused by destruction of the alveolar wall and can lead to the formation of bulla. Bullae are defined as large air-filled spaces with a diameter of 1 cm or greater. Formation of emphysematous bulla can occupy more than one third of the hemithorax and compress adjacent structures. This is significant because these large bulla lack alveolar-capillary interface leading to decreased oxygenation. Bulla is commonly found in the apical location of the upper lung lobes. We present this unusual case of a 67-year old male with a severe history of COPD secondary to smoking is considered for bullectomy of the basilar lung lobe instead of the common apical lobe. Methods: The patient was seen by a pulmonologist and failed medical treatment. After work-up, CT scan showed giant bullae in the basilar lobe instead of the most common apical location. Even with surgery, pulmonary function may not improve. The patient accepts the risks and continued with bullectomy. Results: During the operation, significant bullous lung disease was found, removed, and submitted to pathology. Significant anthracosis was also noted with lung hyperinflation. Following surgery, a post-operative air leak was found and patient developed atrial fibrillation. These complications were managed and inpatient rehabilitation was suggested. Patient preferred to go home and a personalized rehab program was designed for him. Conclusions: In conclusion, despite numerous medical treatments for the COPD patient, surgery may be of benefit to the patient with end-stage COPD. Of the many surgical procedures, giant bullectomy is shown to produce significant immediate functional improvement which persists for at least 3 years in individuals who are carefully selected.Item The Immedicate Effect of OMT on a COPD Population: A Pilot Study(2006-05-01) Som, Mousumi; Kimberly Fulda; John LicciardoneSom, Mousumi, M.S. The Immediate Effect of OMT on a COPD Population: A Pilot Study. Master of Science (Clinical Research and Education OMM), May 2006, 81 pages, 3 figures, references 45 titles. Objective: Chronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of morbidity and mortality in the United States costing approximately 32 billion dollars yearly. COPD cannot be cured, and existing modalities are limited. This study explored the use of Osteopathic Manipulative Treatment (OMT) on pulmonary function and alveolar ventilation. Methods: this prospective, randomized single blinded pilot study included 21 subjects with two interventions: OMT and no intervention. Subjects were 40 to 80 years of age with a clinical diagnosis of COPD. Primary outcome measures included pulmonary function values: FVC, FEV1, FEV1/FVC, RV, TLC. Secondary outcome measures included alveolar ventilation measured by pulse oximetry. Results: No statistically significant results were observed. Clinically relevant trends indicated a potential impact of OMT on COPD subjects. This study was funded by the Osteopathic Research Center (ORC) and approved by the UNTHSC Institutional Review Board. Conclusions: This study demonstrated the feasibility of conducting research on COPD subjects by the ORC. Because of the small sample size, no conclusive statements can be made determining the efficacy of OMT on pulmonary function and alveolar ventilation.