Browsing by Subject "Osteopathic Manipulation"
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Item Osteopathic Manipulative Treatment for Postoperative Nausea and Vomiting(2008-05-01) Schrick-Senasac, Simon L.; Hollis King; Kimberly Fulda; Monte TroutmanSchrick-Senasac, Simon L., Osteopathic Manipulative Treatment for Postoperative Nausea and Vomiting. Masters of Science (Clinical Research and Education, Osteopathic Manipulative Medicine), May, 2008, 95 pp., 9 tables, 7 illustrations, bibliography, 68 titles. Purpose: Despite advances, no therapy has been able to prevent postoperative nausea and vomiting (PONV). This pilot study sought to evaluate the effect of osteopathic manipulation on PONV and to assess the feasibility for reproduction. Methods: Individuals undergoing anesthesia were recruited as subjects. Seventeen subjects completed the study – eight receiving treatment, nine as controls. Nausea and pain visual analog scale (VAS) scores as well as vital signs were collected periodically throughout the study. A post-discharge survey was completed 1 day following treatment. Results: There was no overall reduction of PONV; early emesis was reduced as were 30-minute and peak nausea VAS scores. Additional analysis found pain VAS scores less elevated in treated subjects than controls. This was accompanied by reduced utilization of analgesics following surgery. Conclusions: Incidence of PONV was universally low, likely due to widespread phrophylaxis. Reduction of pain corresponds with research linking manipulation to modulation of neuroendocrine systems. This study demonstrated potential and feasibility for larger reproduction.Item The Effect of Lymphatic Pump Treatment on Anti-Tumor Immune Responses(2011-05-01) McCauley, Lyndsey R.; Hodge, Lisa M.The lymphatic system’s significance in maintaining health has been focused on by the osteopathic medical profession for years. Osteopathic manipulative treatments (OMT), specifically lymphatic pump techniques (LPT), aim at increasing lymphatic circulation and improving the clearance of interstitial fluid, inflammatory agents, and protein from the interstitial space. However, certain osteopathic manipulative techniques, such as LPT, are contraindicated in the presence of cancer with metastatic potential because it is thought that by accelerating the flow of lymph through the lymphatic vessels, tumor cells may metastasize throughout the body via the lymphatics. However, this theory lacks scientific proof. Studies previously conducted by our lab show that LPT increases thoracic duct lymph flow and leukocyte numbers in the rat and significantly decreases solid tumor formation and increases leukocyte concentrations in the lungs of rats with tumors (unpublished data). It is possible that increased lymph flow along with an increased number of circulating leukocytes can improve immune surveillance, providing recognition of and protection against pathogens and disease. Therefore, we hypothesized that administration of LPT would enhance anti-tumor immune responses in the lungs of rats with pulmonary tumors. In order to test this hypothesis, this thesis focused on one specific aim: to determine if LPT enhances leukocyte activation and/or function, thereby enhancing anti-tumor activities, such as tumor lysis and cytokine secretion.