Browsing by Subject "evaluation"
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Item Beginning, Developing, Exemplary: Using a Targeted Grading Rubric to Assess the Information-Seeking Skills of First-Year Medical Students(2010-10-01) Savi, Christine; Bullion, JackItem Development of the Attitudes Toward Osteopathic Principles and Practice Scale (ATOPPS): Preliminary Results(2002-05-01) Russo, David P.Russo, David P., Development of the Attitudes Toward Osteopathic Principles and Practice Scale (ATOPPS): Preliminary Results. Master of Public Health, May 2002, 11 pp., 2 tables, bibliography, 19 titles. Little is known about how student attitudes toward osteopathic principles and practice (OPP) develop and evolve over the course of their osteopathic medical education. Interviews were conducted with osteopathic medical students, osteopathic manipulative medicine (OMM) residents, fellows, and physician specialists. These interviews were summarized in a 39-item instrument administered to 127 students at the completion of their core OMM rotation at UNTHSC-TCOM. Factor analysis of student responses to the 39 candidate items yielded two interpretable factors. 14 of the original 39 statements were eliminated and the smaller second factor was dropped. Factor 1 contained items reflecting both positive and negative attitudes toward the application OPP in patient care, medical education, and professional distinctiveness. Two internal consistency estimates of reliability were computer for the revised 25-item ATOPPS. Estimates for the split-half coefficients for part 1 were .89, for part 2 was .87; the Spearman-Brown coefficient alpha was .93Item Effect of 2018 American College of Cardiology/American Heart Association Guideline Change on Statin Prescription for People Living with HIV(Elsevier B.V., 2023-03-28) Pan, Meng; Agovi, Afiba Manza-A.; Anikpo, Ifedioranma O.; Fasanmi, Esther O.; Thompson, Erika L.; Reeves, Jaquetta M.; Thompson, Caitlin T.; Johnson, Marc E.; Golub, Vitaly; Ojha, Rohit P.The American College of Cardiology (ACC)/American Heart Association (AHA) guidelines were updated in 2018 to explicitly recommend statin use for primary cardiovascular disease prevention among people living with HIV (PLWH), but little is known about the effect of this guideline change. We aimed to assess the effect of the 2018 ACC/AHA guideline change on statin prescription among PLWH. We used data from an institutional HIV registry to identify PLWH aged 40-75 years, engaged in HIV care between June 2016 and May 2021, had a LDL cholesterol between 70 and 189 mg/dl, 10-year atherosclerotic cardiovascular disease (ASCVD) risk score >/=7.5%, no prior statin prescription, and no history of diabetes or ASCVD. Our outcome of interest was a new statin prescription within 12 months of eligibility. We estimated standardized risk difference (RD) with 95% confidence limits (CL) by comparing prescription probabilities before and after guideline change. Our study population comprised 251 PLWH (171 before, 80 after the guideline change), of whom 57% were aged <55 years, 82% were male, and 45% were non-Hispanic black. The standardized 12-month statin prescription risk was 43% (95% CL: 31%, 60%) after the guideline change and 19% (95% CL: 13%, 26%) before the guideline change (RD = 25%, 95% CL: 9.1%, 40%). Our results suggest that the 2018 ACC/AHA guideline change increased statin prescription among PLWH, but a sizable proportion of eligible PLWH were not prescribed statin. Future studies are needed to identify strategies to enhance implementation of statin prescription guidelines among PLWH.Item Evaluation of Spanish Cancer Prevention Education Materials: How Well is the Message Being Received(2006-08-01) Rodriguez, Donna; Gonzalez, Adela; Lurie, SueRodriguez, Donna. Evaluation of Spanish Cancer Prevention Education Materials: How Well is the Message Being Received. Master of Public Health (Community Health), August 2006, 161 pp., 5 tables, 4 charts, 2 titles. The study was conducted to evaluate existing cancer prevention education materials created by Parkland Health & Hospital System to determine the cultural appropriateness and readability for the growing Spanish-speaking Hispanic population in Dallas County. The evaluation focused exclusively on Spanish materials with cancer prevention messaging related to improved nutrition and increased physical activity. Data was collected through two separate series of focus groups with Hispanics and health professionals. The Fry Graph Method was applied to the materials as an additional readability measurement. Results of the evaluation demonstrated a need for Parkland to engage Hispanics in pre-testing and revision of existing Spanish materials; establish strategic partnerships to assist with understanding literacy needs; and implement educational programs that complement materials.Item The Development and Evaluation of an Oligonucleotide Probe for Use in Quantifying Human Mitochondrial DNA Using the Quantiblot Human DNA Identification Kit(2003-07-01) Cooksley, Joseph David; John Planz; Joseph Warren; Arthur EisenbergCooksley, Joseph David, The Development and Evaluation of an Oligonucleotide Probe for Use in Quantifying Human Mitochondrial DNA Using the Quantiblot Human DNA Identification Kit. Master of Science (Forensic Genetics), August 2003, 93pp., 3 tables, 14 figures, 1 appendix, references, 17 titles. Nucleotide sequences from coding regions in the mitochondrial DNA genome were evaluated for use in designing an oligonucleotide probe specific to humans that could be used with Quantiblot Human DNA Identification kit from Applied Biosystems. Two probes were designed and evaluated using the conditions, reagents, and protocols recommended in the kit instructions, as well as with less stringent conditions than those recommended in the kits instructions. Probe 1 bound to amplified mtDNA at low stringency conditions, with greater probe amount, with heat denaturation of the probe, and more HRP-SA enzyme conjugate added than recommended in the protocol. Probe 1 did not hybridize to mtDNA extracted from a buccal swab, bloodstain cards, or a whole blood sample. Probe 2 did not show any hybridization to mtDNA when evaluated.Item Validation of Applied Biosystems 3130xl Genetic Analyzer for Human mtDNA: An Evaluation of Three Amplification Series(2006-08-01) David, Jamalia Junelle; Joseph Warren; John Planz; Arthur EisenbergThe introduction of a new instrument into an accredited laboratory requires a documented internal validation. Validations typically include sensitivity, precision, and mixture studies. These tests assess the reliability and efficiency of the instrument and allow for interpretation guidelines to be established. This project consisted of a validation of Applied Biosystems’ 3130xl Genetic Analyzer and an evaluation of three mitochondrial DNA amplification primer sets for the control region. The validation was designed to evaluate the efficacy, robustness, and working limitations of the 3130xl instrument by performing a sensitivity study. A sensitivity study was performed using DNA sample dilutions, which were quantified using ABIs Quantifiler system to measure the amount of total nuclear DNA content in the samples. The samples were amplified on the GeneAmp PCR System 9700 in triplicate to evaluate stochastic activity. Three different primer sets were utilized which allow for the amplification of different regions of the human mitochondrial genome control region. After amplification, the quality and quantity of the DNA in all the samples was assessed using the Agilent 2100 BioAnalyzer, and subsequent sequence analysis was performed on the 3130xl Genetic Analyzer. Preliminary work has begun on a mixture study, but due to lack of time and reagents, this study was not completed and will have to be performed at a later date. All sequence data from the sensitivity study was evaluated using Sequencher version 4.1.4Fb19