Browsing by Subject "men"
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Item Differences in the Rates of Cardiovasular Surgical Procedures in Men and Women with Coronary Heart Disease in the State of Texas(2003-02-01) Moreland, Matthew C.; Muriel Marshall; Doug A. MainsMoreland, Mathew, Differences in the rates of cardiovascular surgical procedures between men and women with coronary heart disease in the state of Texas. University of North Texas Health Science Center, School of Public Health, February 2003, 19pp., 3 tables, references, 23 titles. Data for the Texas Health Care Information Council was analyzed to identify the difference in the rates of invasive cardiovascular procedures performed on men and women among 411 Texas hospitals with the diagnosis of coronary heart disease in 1999. In all, 150,361 cases were compared for differences between gender, race, age and type of invasive cardiovascular procedure using chi-square test. Frequencies were tabulated for age, race and gender. Invasive cardiac procedures were differentiated by type: coronary angiography and coronary revascularization. Between the ages of 45 and 79 women were more likely to have angiography performed than men in the same age group. However, young (30-44) and elderly (80+) men were more likely to receive angiographic procedures when presenting with the same symptoms as women. Also, men of all ages and races were more likely to receive revascularization procedures (PTCA, CABG) than women when presenting with coronary heart disease symptomology. Additionally, men between the ages of 35 and 49 received twice the number of revascularization procedures than women. These findings identified patterns of treatment with defined differences between gender which may be attributed to external factors versus a true gender bias.Item Health Risk, Behavior and Attitudes of Urban African American Men Toward Prostate Cancer Screening(2006-05-01) Samuel, Prattus; Sue Lurie; Kristine Lykens; Sejong BaeSamuel, Prauttus K., Health Risk, Behavior and Attitudes of Urban African American Men Toward Prostate Screening. Master of Public Health (Community Health), May 20, 2006, 84 pp., 10 tables, 1 illustration, 72 references. In Texas, prostate cancer is the second leading cause of cancer death among non-Hispanic whites and African American (AA) males. This thesis addresses the research questions: what psycho-social characteristics associated with men who participate in prostate screening? What psycho-social and clinical characteristics are associated with reported risk factors? Focus groups were conducted to identify attitudes, perceptions and health beliefs of African American men’s early detection behavior. Existing data from a prostate screening program in Dallas County, Texas was analyzed to determine associations of demographic variables, risk factors variables and screening participation for each subgroup with AA as the group of interest. Comparison of responses and data analysis provided the framework for a conceptual model.Item Patterns of Primary Surgical Procedures Among Men Admitted to Texas Hospitals with a Diagnosis of Prostate Cancer(2001-12-01) Galdiano, Rosemary; Antonio Rene; Doug A. Mains; Sue LurieGaldiano, Rosemary, Patterns of primary surgical procedures among men admitted to Texas hospitals with a diagnosis of prostate cancer. Master of Public Health (Epidemiology), December 2001, 28 pp., 3 tables, 4 illustrations, references, 21 titles. Data for the Texas Health Care Information Council was analyzed to identify the patterns of surgical procedures among men admitted to 114 Texas hospitals with a diagnosis of prostate cancer in 1999; and to determine whether these patterns varied by race and age. In all, 4,608 cases were compared for differences between age, race and type of surgical procedure using Pearson’s chi-square test. Frequencies were tabulated for age, race, length of stay, type of surgery, and type of insurance. Radical prostatectomy and transurethral resection of the prostate are the most common procedures performed. Black and Hispanic men less than 45 years old were more likely to receive radical prostatectomy than whites. Transurethral resection of the prostate (TURP) is most commonly performed in men 75 years and older with higher proportions among black and Hispanic men. Younger men (ageyears) who received TURP were more likely to be white. White men between the ages of 45 and 84 were more likely to receive perineal prostatectomy. These findings identified patterns of treatment with defined differences between age and race.Item δ-2 Opioid receptor plasticity and GM-1(2005-05-01) Davis, Shavsa; Caffrey, James; Mallet, Robert T.; Singh, Meharvanδ-2 Opioid receptor plasticity and GM-1. Shavsha Davis, Masters of Science (Biomedical Sciences), May 2005, 56 pp, 3 tables, 10 figures. The native cardiac enkephalin, methionine-enkephalin-arginine-phenylalanine (MEAP) altered vagally induced bradycardia when introduced into the sinoatrial (SA) node by microdialysis. The responses to MEAP were bimodal in character with lower doses enhancing bradycardia while higher doses suppressed bradycardia. The opposing vagotonic and vagolytic effects were mediated respectively by δ-1 and δ-2-subtypes of the same δ-opioid receptor. The opposing responses were blocked by sub-type specific antagonists. When the mixed agonist, MEAP was evaluated after treatment with the monosialosyl ganglioside, GM-1, the δ-1-mediated vagotonic response was enhanced and the δ-2 mediated vagolytic response independent of a coincident increase in competing the δ-1-mediated vagotonic activity. The selective δ-2-agonist deltorphin was introduced into the SA node by microdialysis to evaluate initial δ-2-vagolytic responses. The right vagus nerve was stimulated and the expected decline in heart rate was significantly attenuated by deltorphin. GM-1 was then perfused into the nodal interstitium for one hour without a significant change in vagal transmission. Following GM-1, deltorphin was reintroduced and a clear attenuation of the deltorphin’s vagolytic response was observed. Similar results were obtained in time controls when GM-1 was omitted. In both cases the δ-1 selective antagonist 7-benzylidenaltrexone (BNTX) failed to restore the vagolytic response when added afterward. However when added to the time controls early in the protocol, BNTX completely prevented the loss in the vagolytic response. When both the intial deltorphin and GM-1 were omitted the vagolytic response was significantly improved. In summary, the initial study with the mixed agonist, MEAP suggested that GM-1 reduced the δ-2-vagolytic response. This was confirmed when the relatively selective δ-2-agonist, deltorphin, was substituted for MEAP. Subsequent protocols suggested that deltorphin and GM-1 produced qualitatively similar losses in the vagolytic response that were not restored by subsequent δ-1-receptor blockade. Thus, the attenuation of the δ-2 response was not due to the addition of completing δ-1-mediated vagotonic activity. The elimination of the deltorphin mediated attrition of the δ-2 response by the BNTX indicated that the declining response was mediated by δ-1-receptors. Thus GM-1, deltorphin, and time all interact to modify subsequent δ-2-mediated vagolytic responses. The specific contribution of deltorphin in this process was mediated by the activation of δ-1-receptors. Whether deltorphin has intrinsic δ-1 activity or causes the release of an endogenous δ-1 agonist is unclear. The specific mechanism by which the δ-1 and δ-2 opioid receptors interact likewise remains to be determined.