Browsing by Subject "research"
Now showing 1 - 11 of 11
- Results Per Page
- Sort Options
Item A Novel Curriculum: Integrating Anatomy, Osteopathic Principles and Practice, and Clinical skills.(2011-05-01) Colston, John S.; Cruser, des AngesThe purpose of this project was to create and test a novel curricular model integrating anatomy, osteopathic principles and practice, and clinical skills. The curricular model was created through collaborative effort with a multi-discipline advisory group. The model’s effectiveness was assessed in two separate learning events involving medical students and pre-medical students. Knowledge assessments and opinion surveys distributed pre and post-learning event demonstrated a positive trend toward knowledge acquisition and support of the curricular model. Implementation of the novel curriculum was successful, producing desired learning outcomes and demonstrating the value of integrating clinical context with basic sciences. Further research and implementation of a more complete version of the model is warranted.Item Comparing Site Management of a NIH versus Industry Sponsored Study: CTSN (Surgical Interventions for Moderate Ischemic Mitral Regurgitation) Trial versus DEEP (Dual Epicardial Endocardial Protocol for Persistent and Longstanding Atrial Fibrillation) Trial(2010-12-01) Ong, Jennifer K.; Patricia GwirtzThe management of a clinical trial requires the coordination of a number of tasks concurrently. Every study has its own individual difficulties and concerns that a research team must work around in order to get a study started and begin subject enrollment. The Baylor Research Institute is participating as a research site for both the CTSN and DEEP studies. Each study is funded by a different type of sponsor, which includes the National Institutes of Health and AtriCure. The two studies were followed from the early stage of site selection up until the point of subject enrollment. The CTSN and DEEP trials provided insight as to how to successfully manage the start-up of both types of studies, demonstrating the delays and difficulties that may arise as a clinical trial agreement approaches execution.Item Converting from Paper-Based to Electronic Data Capture and Record Keeping in Clinical Trial Management: Benefits, Challenges and Practical Considerations(2015-12-01) Castle, Colton; Gwirtz, Patricia A.; Bell, April M.; Hodge, Lisa M.Clinical research has lagged behind the technological advance of other healthcare fields. Most investigational sites depend on a paper‐based data capture and record retention system. This practicum project examined the various benefits and challenges of electronic data capture and electronic record keeping systems. Electronic systems can improve data integrity, reduce trial cost and increase efficiency in the course of a clinical trial. However, electronic systems can also pose some challenges, including implementation and training cost, decreased productivity, and issues with data security and health record privacy. This project discussed some practical considerations for investigational sites transitioning to electronic systems. These aims were accomplished by review of the literature and consulting investigational sites through an email questionnaire.Item Improvement of Data Quality through Source Data Verification in Physical Therapy Research(2014-12-01) Pollard, Kalyssa M.; Robert T. Mallet; Peter B. Raven; Craig GarrisonIt is imperative to minimize errors in essential data to achieve maximum reliability in a research study. The primary objectives of this practicum were to identify the advantages and disadvantages of using clinical trial management software in physical therapy research studies and to determine the ability of that software to improve data quality and therefore research validity. Using source data verification within three research studies at the site, 480 data points were verified retrospectively and 428 were verified prospectively. Following the use of the software, there was a significant reduction in multiple types of data errors at each subject research visit, with an overall error reduction of 86%. The largest limitation of the clinical trial management software is the time requirement for implementation and continuation in each enrolling research study at the site. Alternate electronic management systems should be evaluated for feasibility and improved data quality at the research site.Item Interdisciplinary Research in Alzheimer's Disease and the Roles International Societies Can Play(JKL International, 2021-02-01) Tan, Shawn Zheng Kai; Zhao, Robert Chunhua; Chakrabarti, Sasanka; Stambler, Ilia; Jin, Kunlin; Lim, Lee WeiAn ever-increasing ageing population has elevated Alzheimer's disease to be one of the biggest challenges in modern medicine. Alzheimer's disease is highly complex, and we are still no closer to understanding the causes, let alone an effective treatment. The lack of good experimental models and lack of critical understanding has led to high failure rates of clinical trials with high associated costs, as well as difficulties in implementing treatments. The multifaceted nature of this disease highlights the need for an interdisciplinary approach to address these concerns. In this essay, we suggest how collaborative work can be useful in addressing some of the above issues. We then propose that international organisations and publishers need to support interdisciplinary research by creating platforms, lobbying funders, and pushing for interdisciplinary publications. We further highlight some of the issues involved in implementing these suggestions and argue that willpower of the research community, together with a re-evaluation of evaluation metrics and incentive systems, are needed in order to foster interdisciplinary research. Overall, we emphasise the need for interdisciplinary research in Alzheimer's disease and suggest that international societies should play a huge role in this endeavour.Item Medicare 2005 Demonstration Project: Patient Reporting of Nausea Symptoms and Its Impact on Improving Quality of Patient Care(2006-01-01) Mueller, Brett H.; Rustin Reeves; Ray Page; Walter McConathyFor the completion of the requirements for my Masters degree in clinical research management, I interned under the mentorship of Ray Page, D.O., Ph.D., at the Center for Cancer and Blood Disorders. While at this site, I worked on completing my retrospective chart review research project while also gaining clinical exposure in medical and radiation oncology, observing different aspects of running and managing a medical practice, and learning how to run and manage clinical trials as a future principal investigator. The focus of my internship practicum was to analyze the effectiveness of the 2005 Oncology Demonstration Project. One-hundred thirty three patient charts were identified for this study because as some point during the 2005 year, the patient reported serious symptoms of nausea and vomiting. Over 5,000 patient notes that were documented during the 2005 year were reviewed for the one-hundred and thirty three patient population. Substantial data was collected regarding the ability of the clinicians’ and nurses’ effectiveness in administering nausea and vomiting care with, and without, the 2005 Oncology Demonstration Project. Additional activities during this internship includes shadowing DR. Page, shadowing and learning from the clinical coordinators at the Center, assisting the clinical manager with regulatory binder filling, protocol review, creating a study budget, and participating in, and helping in many other facets of clinical research carried out at the Center for Cancer and Blood Disorders.Item Promoting Good Clinical Practice: Application of Regulatory Binders in a Physical Therapy Research Setting(2012-12-01) de Guzman, Maria-Racella; Patricia GwirtzThe American Physical Therapy Association, which has become one of the most recognized organizations representing the profession, continues to report the expansion of research in the field. As part of the Vision 2020 strategic plan, basic clinical research is mentioned to be an element essential to the physical therapy profession.12 The science behind physical therapy has existed for years with research starting in the early 1940s. This included the start of the clinical trials for the Salk vaccine to eradicate polio in the United States by the 1960s.13 According to the APTA, physical therapy is “a dynamic profession with an established theoretical and scientific base and widespread clinical application in the restoration, maintenance, and promotion of optimal physical functions”.14 The term “physical therapy” is also synonymous with the word “physiotherapy”. The practitioner of PT is known as a physiotherapist or a physical therapist. Physical therapists undergo proper higher education, licensure, and continuing education courses to maintain their role in the most current and up-to-date techniques and services.14 In addition, physical therapists assume a leadership role in patient rehabilitation, prevention, and health maintenance. Lastly, physical therapists help in the development of health care policy by ensuring that services of PT are available, accessible, and optimal.14 Minimal knowledge exists regarding how federal regulations apply to physical therapy research, but there is the justifiable assumption that all federal regulations should apply. Only a modest recognition is identified from the local IEC/IRB committees that overlook human subject clinical trials in physical therapy. The 2011 strategic plan of the Section of Research (SOR) in the APTA emphasizes the effort of increasing research education opportunities, but does not overlook the responsibility of the physical therapy researcher in practicing good clinical practices for the protection of human subjects in research trials.12 Twenty-first century medicine strives to evolve into an evidence-based practice, requiring real evidence that the determined way of treatment is the best option for the patient.15 The APTA has made recognition on its website that the PT profession should equally do the same. The key topic of implementing evidence-based practice in PT is emphasized in the Clinical Research Agenda. The goal of the APTA is to guide every practicing PT to understand that research is important to their clinical practice. Younger generation physical therapists should participate in research projects so that the future of PT practice is built upon factual evidence rather than experience.16 The main goal is that research should establish clinical practice, and that treatment should be decided upon evidence. Lastly, research evidence should be valid. Valid and qualitative evidence in research is important to physical therapy research. “Quality,” defined by the ISO 9000 addresses this as a set of standards in which an organization fulfills customer quality requirements and applicable regulatory requirements.17 Aiming to enhance customer satisfaction and achieving continual improvement are also acknowledged in the ISO. Quality evidence is important in clinical trials because the core components of research help ensure that patient protection follow the compliance of ICH GCP, and validates the integrity of data. The customers of clinical trials are those that benefit from the development of drugs, devices, and methods of preventative medicine, whether they are the research subjects, patients with a particular illness for which the study is being investigated for, physicians treating the patients, or for society.18Item Research Participants' Beliefs and Attitudes Towards Clinical Research Studies(2013-05-01) Thamby, Rohan; Robert T. MalletThe difficulties of clinical trial recruitment are known, but solutions are not well characterized which leads to recruiting research subjects as a major reason for trial inefficiency. The goal of this practicum project was to survey former and current research patients of Texas Pulmonary & Critical Care Associates, P.A. (TPCCC) to optimize recruitment strategies for the TPCCC Research Center by examining their beliefs and attitudes towards research. The results suggest that patients have a generally positive attitude towards clinical research and join for their improvement and benefitting others. There is a strong agreement that former and current patients would recommend others to participate in research and as far as drawbacks, there was no significant drawback experienced. Internet use was more prevalent in patients over the age of 65 and while interest in using the internet to learn more about clinical research was not overwhelming, contact through the internet by e-mail was desired along with telephone contact. Categorization of the participants’ responses may aid the TPCCC research center in developing strategies to improve recruitment.Item Richards, David M., D.O. (1989)(1989-08-31) Richards, David M.; Alter, JudyPresident of TCOM since 1985, Dr. Richards joined the college as vice president of academic affairs in 1981. Under his administration emphasis has been placed on academic excellence and a continued effort toward basic and clinical research. Interviewed by Judy Alter, August 31, 1989Item Secondary Science Curriculum: Developing a Browser-Based Constructive Ecosystem(2004-08-01) Barrier, Ame R.; Reeves, Rustin; Shores, Jay H.; Rudick, Victoria L.Barrier, Ame R., Secondary Science Curriculum: Developing a Browser-Based Constructivist Ecosystem. Master of Science Education (Biomedical Sciences), August, 2004, 46pp, 1 software program, bibliography, 33 titles. The internship practicum report explores current research on the plausibility of incorporating technology based on guided inquiry into K-12 classrooms to increase student science achievement. Part of the practicum report is browser-based software designed for teaching an ecosystems unit and includes the materials for use in a guided inquiry classroom. Can browser-based science instruction designed along a guided inquiry approach increase student achievement in science education and be quantified when compared to didactic classroom methods? The practicum report and the materials developed are designed to provide a means for the eventual testing of technology infused guided inquiry against traditional didactic teaching in the K-12 science classroom and begin to answer this question.Item Turner, James, Ph.D.(1994-04-06) Turner, James; Hailey, BlakeDr. Turner, Professor and Chairman of the Anatomy & Cell Biology Department, recounts his work in eye disease research and his plans for future research. Interviewed by Blake Hailey, April 6, 1994