Browsing by Subject "research design"
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Item A Retrospective Analysis and Curricular Mapping Assessment of Student Engagement in Research Design in Classes Offered by the College of Pharmacy at University of North Texas Health Science Center at Fort Worth(2016-12-01) Baskaran, Karthikeyan; Jerry W. Simecka; Patrick Clay; Victor V. UteshevThe purpose of this study is to perform a retrospective analysis and curricular assessment to identify classes at the University of North Texas System College of Pharmacy (UNTSCP), which provided student engagement in research design. The first stage of this quality assurance project involved the use of content analysis to review class syllabi and materials for the potential opportunity for student engagement in research design at UNTSCP. The second stage of this quality assurance project will involve the administration of online questionnaires to students and faculty of UNTSCP. The final stage of this quality assurance project will involve conducting face-to-face interviews with the faculty of UNTSCP. Upon completion of the first stage, we gained new insight into the student learning experience and found the opportunity for student engagement in research design to have been dispersed in a variety of core and elective classes at UNTSCP.Item Improvement of Data Quality through Source Data Verification in Physical Therapy Research(2014-12-01) Pollard, Kalyssa M.; Robert T. Mallet; Peter B. Raven; Craig GarrisonIt is imperative to minimize errors in essential data to achieve maximum reliability in a research study. The primary objectives of this practicum were to identify the advantages and disadvantages of using clinical trial management software in physical therapy research studies and to determine the ability of that software to improve data quality and therefore research validity. Using source data verification within three research studies at the site, 480 data points were verified retrospectively and 428 were verified prospectively. Following the use of the software, there was a significant reduction in multiple types of data errors at each subject research visit, with an overall error reduction of 86%. The largest limitation of the clinical trial management software is the time requirement for implementation and continuation in each enrolling research study at the site. Alternate electronic management systems should be evaluated for feasibility and improved data quality at the research site.Item Physiologic and Anatomic Changes in Carpal Tunnel Syndrome: Is Osteopathic Manipulative Treatment an Effective Non-Surgical Alternative Therapy?(2005-05-01) White, Heath D.; Williams, Stuart; Cruser, des Anges; Stoll, ScottWhite, Heath D., D.O., M.S. Physiologic and Anatomic Changes in Carpal Tunnel Syndrome: Is Osteopathic Manipulative Treatment an Effective Non-surgical Alternative Therapy? Master of Science (Clinical Research and Education – OMM), May 2005, 110 pp., 4 tables, 5 figures, references, 46 titles. Objective: Carpal tunnel syndrome (CTS), caused by compression of the median nerve within the carpal tunnel, has a prevalence that ranges between 0.53 and 16.3 with medical costs exceeding $2 billion annually. The goal of this clinical trial was to assess for physiologic and anatomic changes in CTS in response to OMT. Physiologic changes were measured with nerve conduction studies (NCS). Anatomic changes were measured with magnetic resonance imaging. Methods: This prospective, randomized, controlled, blinded clinical trial phased to evaluate 50 subjects randomized between two treatment groups, OMT and placebo sub-therapeutic ultrasound. Eligibility criteria included adults between 21 and 70 with a clinical diagnosis of CTS and increased conduction latency of the median nerve. Outcome measures were median motor and sensory conduction distal latencies. Subjects received six treatments. NCS were conducted at entry to the study (baseline), midpoint, and endpoint. Results: Thirty-seven of a planned 50 subjects were randomized to groups. Thirty-one subjects were included in the final data analysis. Preliminary analysis found no significant difference in NCS values over the three testing intervals. Evaluation for effect(s) of multiple treatment providers by analyzing the single treatment provider with the greatest number of subjects found significant improvement in some NCS values for the OMT group. This study was funded by the Osteopathic Research Center, and approved by the UNTHSC Institutional Review Board. Conclusions: The results of this preliminary analysis indicate the possibility for improvement of CTS with OMT, but no conclusive statements about the efficacy of OMT can be made. This preliminary study enabled us to identify multiple areas in the research design and methodology that may be improved, and provides the framework for future studies.