Browsing by Subject "sex"
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Item Association between magnesium intake and cognition in US older adults: National Health and Nutrition Examination Survey (NHANES) 2011 to 2014(Alzheimer's Association, 2022-02-01) Tao, Meng-Hua; Liu, Jialiang; Cervantes, DianaIntroduction: Identifying nutrition- and modifiable lifestyle-based risk factors for cognitive decline and dementia may contribute future primary prevention strategies. This study aimed to evaluate the associations between magnesium intake and cognition in older adults in the United States. Methods: Based on the National Health and Nutrition Survey (NHANES) between 2011 and 2014, the study included 2508 participants aged 60 years and older. Linear regression models were used to examine the association of total magnesium intake with cognition. Results: After adjusted demographic and other confounding factors, intakes of energy and total calcium, and serum vitamin D level, higher intake of total magnesium was independently associated with 0.15 higher global cognitive z-score (95% confidence interval, 0.02 to 0.28 for highest vs. lowest quartile, P trend = .037). The positive association of total magnesium intake with global cognition was primarily presented among women, non-Hispanic Whites, and those with sufficient serum vitamin D levels (≥50 nmol/L), although interactions were not significant. There were no clear linear associations for global cognition with serum vitamin D level. Discussions: Our findings suggest that high magnesium intake alone may improve cognition in older adults, particularly among non-Hispanic Whites and subjects with sufficient levels of serum vitamin D. Further studies are needed to confirm the findings.Item Gender Differences: Making the Decision to Seek Treatment for Symptoms of Acute Myocardial Infarction(2000-05-01) Borski, Catherine A.; Shelia Reed; Joseph Doster; Claudia CogginBorski, Catherine A., Gender Differences: Making the decision to seek treatment for symptoms of acute myocardial infarction. Masters of Public Health (Health Behavior), May, 2000, 57 pp., reference list, 37 titles. The purpose of this study was to investigate the problem: Do differences in interpretation and response to symptoms of AMI account for additional delay in seeking treatment in women compared with men? The sample consisted of 50 (21 women, 29 men) post-myocardial infarction patients in a large, non-profit, teaching hospital in central Texas. Participants were interviewed within 72 hours of admission using the Revised Response to Symptoms questionnaire. In this study, it was found that there was a statistically significant difference between the cognitive and emotional processes that men and women use when making the decision to seek treatment for symptoms of AMI.Item Sex and strain differences in renal hemodynamics in mice(Wiley Periodicals, Inc., 2023-03-23) Tao, Yu; Young-Stubbs, Cassandra M.; Yazdizadeh Shotorbani, Parisa; Su, Dong-Ming; Mathis, Keisa W.; Ma, RongThe present study was to examine sex and strain differences in glomerular filtration rate (GFR) and renal blood flow (RBF) in C57BL6, 129/Sv, and C57BLKS/J mice, three commonly used mouse strains in renal research. GFR was measured by transdermal measurement of FITC-sinitrin clearance in conscious mice. RBF was measured by a flow probe placed in the renal artery under an anesthetic state. In C57BL6 mice, there were no sex differences in both GFR and RBF. In 129/Sv mice, females had significantly greater GFR than males at age of 24 weeks, but not at 8 weeks. However, males had higher RBF and lower renal vascular resistance (RVR). Similar to 129/Sv, female C57BLKS/J had significantly greater GFR at both 8 and 24 weeks, lower RBF, and higher RVR than males. Across strains, male 129/Sv had lower GFR and higher RBF than male C57BL6, but no significant difference in GFR and greater RBF than male C57BLKS/J. No significant difference in GFR or RBF was observed between C57BL6 and C57BLKS/J mice. Deletion of eNOS in C57BLKS/J mice reduced GFR in both sexes, but decreased RBF in males. Furthermore, there were no sex differences in the severity of renal injury in eNOS(-/-) dbdb mice. Taken together, our study suggests that sex differences in renal hemodynamics in mice are strain and age dependent. eNOS was not involved in the sex differences in GFR, but in RBF. Furthermore, the sexual dimorphism did not impact the severity of renal injury in diabetic nephropathy.