School of Biomedical Sciences

Three-dimensional variation in maxillary sinus anatomy: Implications for health disparities in sinonasal disease

Kim, Suhhyun (2022-05)

Sinusitis affects approximately 30 million Americans annually and is associated with negative quality of life, overuse of antibiotics, and high healthcare costs. As the maxillary sinus (MS) is the sinus most commonly ...

The Impact of Travel Stressors on the Pathogenesis of Autoimmunity in Female Lupus Mice

Dinh, Viet Q. (2022-05)

Preliminary studies found that an established model of systemic lupus erythematosus, the female NZBWF1 mouse, developed heightened disease severity later in life when shipped to UNTHSC during summer due to travel stressors. ...

Hemodynamic Oscillations: Physiological Consequences and Therapeutic Potential

Anderson, Garen K. (2022-05)

Hemorrhage, or massive blood loss, continues to be a leading cause of preventable death. Therapeutic approaches that protect vital organ function are needed to improve outcomes from hemorrhage. In this dissertation, I ...

Advancing the Role of Thyrotropin-releasing Hormone as a Central Nervous System Agent

De La Cruz, Daniel L. (2022-05)

Effects of Sex, Life Stage, and Specific Blood Meals on Microbiome of Starved Ornithodoros turicata

Brown, Austin R. (2022-05)

Ticks carry and transmit more disease agents than any other arthropod vector. The composition of the microbiome within ticks may influence this ability, but many factors that influence their microbial composition remain ...

Identifying Potential Biomarkers and Clinical Trial Outcomes for Future Clinical Trials for SLC13A5 Deficiency

Cooper, Sydney (2022-12)

Comparing Short-Term Radiographic Outcomes of Cementless Primary Reverse Total Shoulder Arthroplasty Implantation With and Without Augmentation by Humeral Matchstick Autograft: A Retrospective Cohort Study

Ouseph, Alvin (2021-12)

Reverse Total Shoulder Arthroplasty (RTSA) is an arthroplasty procedure that is increasing in incidence in the United States (26). As the incidence of the procedure increases, the gross number of RTSA complications is also ...

Roadblocks in Clinical Research: An Analysis of Common Barriers to the Clinical Research Process

Carter, Anne M. (2022-12)

Deficiencies in the clinical research process can lead to delays, loss of funding, outdated conclusions, and a lack in participation for both volunteers and scientists or clinicians. This project aimed to identify the ...

The Role of LLT1 (CLEC2D, OCIL) in Ewing Sarcoma

Buller, Casey W. (2021-12)

Ewing Sarcoma (EWS) is a pediatric bone cancer that is characterized by a chromosomal translocation giving rise to a neomorphic gene fusion. Although treatment of EWS has a 5-year incident free survival rate of 66%, treatment ...

Oral and gut microbiome in chronic sleep restriction mice models

Trinh, Heather (2020-12)

Reduced sleep quality is a common problem in the US, linked to increased risk for several disease conditions. Current evidence indicates an association between the gut microbiome and sleep modulation. With the ease of ...

Aging impairs regulatory T cells to affect the mouse model of late-onset multiple sclerosis

Wang, Weikan (2022-08)

Although multiple sclerosis (MS) primarily onsets in young adults, it can also develop in the elderly, which is termed late-onset (aged) MS. CD4+ Foxp3 + regulatory T (Treg) cells play an ameliorative role in severity of ...

Massage Application to Decrease Anesthetic Spread in Supraclavicular Blocks: A cadaveric study

Coffman, Taylor G. (2022-08)

Examining the skin and workplace microbiome following the return to the University of North Texas Health Science Center after self-isolation

Khichi, Ophelia J. (2021-08)

The human skin microbiome contains trillions of microbiomes that colonize the human body. It is unknown how social distancing and an increase in handwashing due to the COVID-19 pandemic affect the bacterial communities ...