A RAPIDLY PROGRESSING CASE OF SCHMIDT SYNDROME IN A MALE

Purpose: The purpose of this case presentation is to describe a very unusual presentation of Schmidt Syndrome, a rare multi-organ autoimmune disease. The case is unusual in that the disease rapidly progressed to multi-organ failure and presented in a male; both of these factors are very rare for Schmidt Syndrome. This is an extremely unique case and reporting the clinical management, findings, and symptoms involved in the case will provide supporting evidence/information for future physicians as this disease is a difficult and often missed diagnosis. Additionally, this case may lead to some new insight into disease process and maybe lead to new management strategies or treatments. Methods: The case presentation was a retrospective chart review of a single patient. The materials included progress notes from primary physicians and consults, lab work, and radiology readings. Results: We discuss diagnosis and clinical management of Schmidt syndrome. Management can be particularly challenging as the effected organs have additional effects on each other. Also discussed is a list of other symptoms that may occur in presentation. Conclusions: This is one of the few cases ever reported of a male with Schmidt syndrome. The rapid progression seen in this case has not previously been linked to affected males. However, this case may indicate that while males are effected less often then females, they may have present with a more severe form of the disease and new management techniques should be investigated to better control such a rampant process.