Gender Differences in Hemoglobin Level at the Onset of Symptoms of Cancer-Related Anemia

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dc.contributor.advisorVictoria Rudick
dc.creatorLevar, Joshua M.
dc.date.accessioned2019-08-22T19:36:23Z
dc.date.available2019-08-22T19:36:23Z
dc.date.issued2003-12-01
dc.date.submitted2014-02-24T07:00:05-08:00
dc.description.abstractLevar, Joshua M., Gender Differences in Hemoglobin Level at the Onset of Symptoms of Cancer-Related Anemia. Masters (Clinical Research Management), December, 2004, 39 pp., 2 tables, 5 illustrations, bibliography, 47 titles. The purpose of this study was to assess whether the previously demonstrated relationship between quality of life and anemia in cancer patients was influenced by gender. Two hundred and fifty one patients of various diagnoses completed the Functional Assessment of Cancer Therapy – Anemia (FACT-An) subscale to measure quality of life. Regression analysis revealed a significant positive correlation between hemoglobin and FACT-An subscale score, as well as a negative correlation between Eastern Cooperative Oncology Group (ECOG) performance status and FACT-An subscale score. Mean comparison demonstrated a significant difference in FACT-An score between patients currently and not currently receiving chemotherapy. An analysis of covariance, controlling for current therapy and ECOG performance status as confounders, found that men score more poorly on the FACT-An within the hemoglobin range of 10.-13.0 g/dL. In conclusion, the normalization of hemoglobin levels improves quality of life; however, gender differences should be taken into account when determining optimal hemoglobin levels.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/26402
dc.language.isoen
dc.provenance.legacyDownloads0
dc.subjectCancer Biology
dc.subjectCell and Developmental Biology
dc.subjectCell Biology
dc.subjectCells
dc.subjectDiseases
dc.subjectLife Sciences
dc.subjectMedical Cell Biology
dc.subjectMedical Sciences
dc.subjectMedical Toxicology
dc.subjectMedicinal and Pharmaceutical Chemistry
dc.subjectMedicine and Health Sciences
dc.subjectOncology
dc.subjectOther Cell and Developmental Biology
dc.subjectPharmacy and Pharmaceutical Sciences
dc.subjectTherapeutics
dc.subjectToxicology
dc.subjectGender differences
dc.subjecthemoglobin level
dc.subjectonset symptoms
dc.subjectcancer-related anemia
dc.subjectfunctional assessment of cancer therapy
dc.subjectanemia
dc.subjectFACT-An
dc.subjectEastern Cooperative Oncology Group
dc.subjectECOG
dc.subjectchemotherapy
dc.subjectoptimal hemoglobin levels
dc.titleGender Differences in Hemoglobin Level at the Onset of Symptoms of Cancer-Related Anemia
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineClinical Research and Education: Osteopathic Manipulative Medicine
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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