The Applicability of Whole Genome Amplification to Minute Quantities of DNA for Forensic Use

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dc.contributor.advisorJoseph Warren
dc.contributor.committeeMemberJohn Planz
dc.contributor.committeeMemberArthur Eisenberg
dc.creatorLeal, Barbara L.
dc.date.accessioned2019-08-22T20:10:18Z
dc.date.available2019-08-22T20:10:18Z
dc.date.issued2004-08-01
dc.date.submitted2014-05-30T08:00:39-07:00
dc.description.abstractThis research study was performed at DNAPrint™ in Sarasota. FL. DNAPrint™ is a private laboratory specializing in Single Nucleotide Polymorphism (SNP) technology. Through the use of this technology, they have been able to map SNPs termed Ancestry Informative Markers. This has allowed them to perform additional research with regards to biogeographical ancestry, identification of an individual's physical traits, as well as pharmacogenomics research. In addition, DNAPrint™ also performs paternity and forensic testing using STR markers. This research study was a preliminary investigation of the applicability of Whole genome amplification (WGA) using the GenomiPhi™ DNA Amplification assay in conjunction with available STR kits. The GenomiPhi™ assay was utilized due to its ease and efficiency. Depending upon the outcome of this project, further studies may be conducted to incorporate WGA for use with both their SNP and STR technology.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/27968
dc.language.isoen
dc.provenance.legacyDownloads0
dc.subjectCell and Developmental Biology
dc.subjectComputational Biology
dc.subjectEquipment and Supplies
dc.subjectForensic Science and Technology
dc.subjectGenetics
dc.subjectGenetics and Genomics
dc.subjectGenetic Structures
dc.subjectHealth Information Technology
dc.subjectInvestigative Techniques
dc.subjectLife Sciences
dc.subjectMedicine and Health Sciences
dc.subjectOther Genetics and Genomics
dc.subjectDNAPrint
dc.subjectprivate laboratory
dc.subjectSingle Nucleotide Polymorphism technology
dc.subjectSNP
dc.subjectancestry
dc.subjectSTR markers
dc.subjectpaternity testing
dc.subjectforensic testing
dc.subjectWGA
dc.titleThe Applicability of Whole Genome Amplification to Minute Quantities of DNA for Forensic Use
dc.typeProfessional Report
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineCell Biology and Genetics
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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