Two Presentations of Neuroglial Heterotopias with Cleft Palate
| dc.creator | Stucki, Brenton | en_US |
| dc.creator | Marcincuk, Michelle | en_US |
| dc.creator.orcid | 0009-0001-0234-0469 (Stucki, Brenton) | |
| dc.date.accessioned | 2024-04-17T17:42:13Z | |
| dc.date.available | 2024-04-17T17:42:13Z | |
| dc.date.issued | 2024-03-21 | en_US |
| dc.description.abstract | Introduction: Neuroglial heterotopias, commonly known as nasal gliomas, are rare masses composed of brain tissue located outside of the cranial vault. These masses are composed of dysplastic glial cells which have lost their intracranial connections and can present as extranasal, intranasal, or mixed masses. They are thought to result from the incomplete closure of the anterior fontanelle between the nasal and frontal bones; this can result in an irregular connection between embryonic ectoderm and neuroectodermal tissue. Although the presentation of a neuroglial heterotopia in a child is uncommon, even more notable is the finding of neuroglial heterotopias visible from a concurrent cleft palate, as this can present additional difficulties in future cleft palate repair and mass excision. Case Presentation: Presented in this report are two cases of a neuroglial heterotopia found simultaneously with cleft palate. Although these lesions are typically considered benign growths, unmanaged neuroglial heterotopias can result in improper craniofacial development resulting in cosmetic complications and airway obstructions. For accurate diagnosis, thorough histological identification of the embryological tissue origins after surgical biopsy should be performed. Although neuroglial heterotopias and other masses of the nasopharynx such as teratomas have similar treatment methods (namely surgical resection), detailed histological evaluation of tissue biopsies allows physicians to properly manage cases such as these post-treatment. Early surgical removal of neuroglial heterotopias are encouraged in order to minimize nasal and craniofacial distortion early in development as well as to slow or prevent further growth of the lesion. Conclusions: Imaging diagnostics, histological evaluation, surgical procedures, and patient management of the two cases are highlighted in the report in an effort to provide more insight into possible differential diagnoses and treatment options to physicians with similar case presentations. | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.12503/32730 | |
| dc.language.iso | en | |
| dc.title | Two Presentations of Neuroglial Heterotopias with Cleft Palate | en_US |
| dc.type | poster | en_US |
| dc.type.material | text | en_US |