Advancing the Role of Thyrotropin-releasing Hormone as a Central Nervous System Agent

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dc.contributor.advisorProkai-Tatrai, Katalin
dc.contributor.committeeMemberProkai, Laszlo
dc.contributor.committeeMemberLacko, Andras G.
dc.contributor.committeeMemberForster, Michael J.
dc.creatorDe La Cruz, Daniel L.
dc.date.accessioned2023-07-14T21:00:36Z
dc.date.available2023-07-14T21:00:36Z
dc.date.issued2022-05
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/32376
dc.language.isoen
dc.subjectTRH
dc.subjectbrain-targeting prodrug design
dc.subjectprolyl oligopeptidase (POP)
dc.subjectlipoamino acid
dc.subjectCNS-drug delivery
dc.subjectallosteric binding
dc.subjectTRH antagonist
dc.subjectTRH receptor
dc.subjecthomology model
dc.subjecthTRHR
dc.subjectdocking
dc.subjectextracellular domain
dc.subjectG protein-coupled receptor
dc.subjectsurface-recognition binding
dc.subject.meshCentral Nervous System Agents
dc.subject.meshThyrotropin-Releasing Hormone
dc.subject.meshProdrug
dc.titleAdvancing the Role of Thyrotropin-releasing Hormone as a Central Nervous System Agent
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentSchool of Biomedical Sciences
thesis.degree.disciplinePharmacology and Neuroscience
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameDoctor of Philosophy

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