Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS

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dc.creatorShetty, Ashok K.
dc.creatorShetty, Padmashri A.
dc.creatorZanirati, Gabriele
dc.creatorJin, Kunlin
dc.creator.orcid0000-0002-1336-348X (Jin, Kunlin)
dc.date.accessioned2022-09-09T14:08:41Z
dc.date.available2022-09-09T14:08:41Z
dc.date.issued2021-09-09
dc.description.abstractRecent double-blind, randomized, controlled trials reported that human umbilical cord-derived mesenchymal stem cell (MSC) infusions in COVID-19 patients with acute respiratory distress syndrome (ARDS) could diminish cytokine storm and lung damage. While these outcomes are significant, additional phase II/III trials are required to validate the efficacy of MSCs to improve the survival of COVID-19 patients with ARDS. Future studies also need to assess the efficacy of MSCs to prevent long COVID.en_US
dc.description.sponsorshipThe authors are supported by grants from the National Institute of Neurological Disorders and Stroke (1R01NS106907-01 to A.K.S.) and the Department of Defense (W81XWH-14-1-0572 and W81XWH-16-1-0480 to A.K.S.). G.Z. is supported by a postdoctoral fellowship from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Government of Brazil.
dc.identifier.citationShetty, A. K., Shetty, P. A., Zanirati, G., & Jin, K. (2021). Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS. NPJ Regenerative medicine, 6(1), 53. https://doi.org/10.1038/s41536-021-00161-z
dc.identifier.issn2057-3995
dc.identifier.issue1
dc.identifier.urihttps://hdl.handle.net/20.500.12503/31697
dc.identifier.volume6
dc.publisherSpringer Nature
dc.relation.urihttps://doi.org/10.1038/s41536-021-00161-z
dc.rights.holder© The Author(s) 2021.
dc.rights.licenseAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceNPJ Regenerative Medicine
dc.titleFurther validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS
dc.typeArticle
dc.type.materialtext

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