Influence of the Carotid Baroreflex on Cerebral Blood Flow During Seated Upright Rest

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dc.contributor.advisorPeter B. Raven
dc.contributor.committeeMemberRobert Mallet
dc.contributor.committeeMemberJames Caffrey
dc.creatorEubank, Wendy L.
dc.date.accessioned2019-08-22T21:47:28Z
dc.date.available2019-08-22T21:47:28Z
dc.date.issued2007-07-01
dc.date.submitted2014-01-14T06:24:04-08:00
dc.description.abstractEubank, Wendy L., Influence of Carotid Baroreflex on Cerebral Blood Flow During Seated Upright Rest. Master of Science (Integrative Physiology), July, 2007, 25 pp., 1 table, 4 illustrations, 34 references. This study tested the hypothesis that sympathetic activation via the carotid baroreflex directly influences cerebral vasomotion during seated upright test. This study also examined the effects of pulsatile neck pressure (NP) and neck suction (NS) during seated upright rest in healthy human subjects. Changes in mean arterial pressure (MAP) and mean middle cerebral arterial velocity (MCA V mean), were measured. The power spectral density (PSD) of MAP of 0.1Hz increased during pulsatile NP and NS. The PSD of MCA V mean at 0.1Hz was much greater during NP than that of NS. There were no significant differences between end-tidal CO2 between each condition. These findings suggest that cerebral vasoconstriction during NP was a result of the autoregulatory response to the NP mediated pulsatile changes in arterial pressure and the NP induced sympathetically mediated vasoconstriction.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/29586
dc.language.isoen
dc.provenance.legacyDownloads0
dc.subjectCardiovascular System
dc.subjectLife Sciences
dc.subjectMedicine and Health Sciences
dc.subjectNervous System
dc.subjectPhysiology
dc.subjectSystems and Integrative Physiology
dc.subjectCarotid Baroreflex
dc.subjectcerebral blood flow
dc.subjectseated upright rest
dc.subjectintegrative physiology
dc.subjectcerebral vasomotion
dc.subjectpulsative neck pressure
dc.subjectneck suction
dc.subjectmean arterial pressure
dc.subjectmean middle cerebral arterial velocity
dc.subjectpower spectral density
dc.subjectautoregulatory
dc.subjectsympathetically mediated vasoconstriction
dc.titleInfluence of the Carotid Baroreflex on Cerebral Blood Flow During Seated Upright Rest
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineIntegrative Physiology
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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