Ancestry Informativeness of Alu Markers in Four Populations Relevant for the United States

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dc.contributor.advisorRanajit Chakraborty
dc.contributor.committeeMemberBobby L. LaRue
dc.contributor.committeeMemberRobert C. Barber
dc.creatorD'Auben, Aislinn G.
dc.date.accessioned2019-08-22T21:24:37Z
dc.date.available2019-08-22T21:24:37Z
dc.date.issued2015-05-01
dc.date.submitted2016-08-05T14:18:05-07:00
dc.description.abstractDetermination of ancestry using DNA markers is an important issue in DNA forensics. The ability to identify an individual’s ancestry could narrow down the pool of possible individuals involved in a crime. Several types of ancestry informative markers (AIMs) have been suggested in the literature. For this study, Alu markers were used for investigating their utility for Caucasian versus African and Caucasian versus Asian ancestry determinations. Three measures of AIMs were calculated for 42 Alu markers. Rank correlations of these three measures were used for investigating if a smaller number of top-ranked loci can improve ancestry determination. The Alu markers chosen for this study were less informative than anticipated but did show potential for ancestry estimation when all 42 markers were used together.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/29311
dc.language.isoen
dc.provenance.legacyDownloads59
dc.subjectMedical Sciences
dc.subjectMedicine and Health Sciences
dc.subjectAlu markers
dc.subjectancestry
dc.subjectUnited States
dc.titleAncestry Informativeness of Alu Markers in Four Populations Relevant for the United States
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineForensic Genetics
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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