A Semi-Automated Methodology for Extraction of DNA from Human Skeletal Remains

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dc.contributor.advisorArthur Eisenberg
dc.creatorMize, Mary L.
dc.date.accessioned2019-08-22T21:24:26Z
dc.date.available2019-08-22T21:24:26Z
dc.date.issued2013-05-01
dc.date.submitted2013-04-29T14:36:05-07:00
dc.description.abstractThe current methodology used by the University of North Texas Center for Human Identification Missing Persons Laboratory (UNTCHI) to recover DNA from skeletal remains is time-consuming, laborious and not readily amenable to automation. The constraints of the current process limit the number of samples that can be analyzed. The results of this study show that extractions performed with the AutoMate Express™ Forensic DNA Extraction System (Life Technologies, Carlsbad, CA) can produce comparable DNA quantity and quality to the current procedure used by UNTCHI. The utilization of the AutoMate Express™ Forensic DNA Extraction System in our operational laboratories would help streamline the process of DNA extraction from human skeletal remains and potentially provide increased amounts of genetic information.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/29309
dc.language.isoen
dc.provenance.legacyDownloads662
dc.subjectGenetics
dc.subjectGenetics and Genomics
dc.subjectMedical Sciences
dc.subjectMedicine and Health Sciences
dc.subjectRobotics
dc.subjectSkeletal remains
dc.subjectDNA
dc.subjectAutomated Extraction
dc.subjectAutomation
dc.titleA Semi-Automated Methodology for Extraction of DNA from Human Skeletal Remains
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineForensic Genetics
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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