In Vitro Effect of CNTF, FGF-9, IL-1α on Human Optic Nerve Head Astrocytes

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dc.contributor.advisorWordinger, Robert J.
dc.contributor.committeeMemberAlvarez-Gonzales, Rafael
dc.contributor.committeeMemberAgarwal, Neeraj
dc.creatorTovar-Vidales, Tara
dc.date.accessioned2019-08-22T21:15:02Z
dc.date.available2019-08-22T21:15:02Z
dc.date.issued2004-08-01
dc.date.submitted2014-04-03T09:42:06-07:00
dc.description.abstractTovar, Tara., In Vitro Effect of CNTF, FGF-9, and IL-1α on Human Optic Nerve Head Astrocytes. Master of Science (Biomedical Sciences), August 2004, 100 pp., 4 tables, 35 illustrations, bibliography, 163 titles. Glaucoma is a leading cause of blindness worldwide. A major risk factor for glaucoma is increased intraocular pressure that leads to pathological changes in the optic nerve head (ONH). Astrocytes within the ONH become activated in glaucoma and may create an environment detrimental to retinal ganglion cell axons. The factors that cause activation of the ONH astrocytes (ONA) are unknown, although there is evidence that CNTF, FGF-9, and IL-1α activate glial cells within the CNS. The purpose of this research was to determine if exogenous CNTF, FGF-9, and/or IL-1α activate human ONH astrocytes.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/29189
dc.language.isoen
dc.provenance.legacyDownloads0
dc.subjectCell and Developmental Biology
dc.subjectCell Biology
dc.subjectCells
dc.subjectChemicals and Drugs
dc.subjectEye Diseases
dc.subjectLife Sciences
dc.subjectMedicine and Health Sciences
dc.subjectOphthalmology
dc.subjectOptometry
dc.subjectOther Cell and Developmental Biology
dc.subjectVision Science
dc.subjectIn vitro
dc.subjecteffect
dc.subjectCNTF
dc.subjectFGF-9
dc.subjectIL-1α
dc.subjecthuman optic nerve head astrocytes
dc.subjectglaucoma
dc.subjectintraocular pressure
dc.subjectoptic nerve head
dc.subjectONH
dc.subjectretinal ganglion cell axons
dc.subjectglial cells
dc.titleIn Vitro Effect of CNTF, FGF-9, IL-1α on Human Optic Nerve Head Astrocytes
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineBiomedical Sciences
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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