Factors Influencing U.S. Women's Willingness for Utilizing Human Papillomavirus Self-Sampling




Garg, Ashvita
Galvin, Annalynn
Griner, Stacey
Rosberger, Zeev
Daley, Ellen
Thompson, Erika


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Purpose. HPV self-sampling is a novel method of HPV testing that is widely accepted in various countries. Recent modifications in the U.S. cervical cancer screening guidelines includes HPV testing and provides HPV self-sampling as another screening option, especially for underserved populations. Due to the scarcity of research regarding the process factors for HPV self-sampling, the current study examines the correlates of the willingness of women to have HPV self-sampling. Methods. A cross-sectional study was conducted among women between the ages of 30-65 years, with no history of hysterectomy (n=812). The outcome variable was a willingness to have HPV self-sampling test (yes/no). Predictor variables included various process factors. Adjusted logistic regression recognized correlates of HPV self-sampling willingness. Results. Higher odds of HPV self-sampling willingness were found among participants who preferred receiving self-sampling information from healthcare providers (OR=2.64; 95%CI 1.54, 4.52) or media (OR=2.30; 95%CI 1.51, 3.48). However, lower odds of self-sampling willingness were found among participants who did not want to pay for the self-sampling kit (OR=0.21; 95%CI 0.14, 0.32) or were not sure which method they preferred for receiving the kit (OR=0.15, 95%CI 0.07, 0.31) as compared to those preferred the mail. Conclusions. Prior to implementing any HPV self-sampling program, it is essential to understand women's preferences for process factors for this screening method for a successful implementation. Strengthening the infrastructural supports can help ensure improved and equitable access to this convenient and private screening method.