A Validation of STRmix™ for Forensic Casework

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dc.contributor.advisorBruce Budowle
dc.contributor.committeeMemberJoseph E. Warren
dc.contributor.committeeMemberPatricia A. Gwirtz
dc.creatorConway, Allison
dc.date.accessioned2019-08-22T21:39:38Z
dc.date.available2019-08-22T21:39:38Z
dc.date.issued2017-05-01
dc.date.submitted2018-08-16T11:42:08-07:00
dc.description.abstractThe interpretation of complex DNA profiles has been a controversial issue in forensic biology. The current methods of interpretation are limited in scope and do not make full use of the data. Efforts have been made to develop software which can incorporate more data and process more calculations than were previously possible. One such program, STRmix™ (Institute of Environmental Science and Research, Porirua, New Zealand), uses a Markov Chain Monte Carlo (MCMC) principle to simulate many different possible profiles and determine the probability of observing a profile in the evidence. A validation of this software is necessary to indicate which situations are appropriate for analysis and define existing limitations.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/29493
dc.language.isoen
dc.provenance.legacyDownloads29
dc.subjectMedical Sciences
dc.subjectMedicine and Health Sciences
dc.subjectSTRmix
dc.subjectDNA
dc.subjectforensic
dc.subjectprobabilistic genotyping
dc.titleA Validation of STRmix™ for Forensic Casework
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.disciplineBiomedical Sciences
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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