Spatial phylogeography and correlation between genetic and geographical distance in Trypanosoma cruzi and its vectors of the genus Triatoma from Texas.

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dc.contributor.advisorMichael Allen
dc.creatorMitchell, Elizabeth A.
dc.date.accessioned2019-08-22T19:55:02Z
dc.date.available2019-08-22T19:55:02Z
dc.date.issued2013-08-01
dc.date.submitted2013-08-05T13:54:06-07:00
dc.description.abstractThis study proposes to describe the phylogenetic relationship among Triatoma species that carry Trypanosoma cruzi and between T. cruzi isolates, present in Texas. Additionally, it evaluates any correlation between geographical location of Triatoma collection and genotype of T. cruzi isolates, and the distribution of T. cruzi genotypes relative to ecological variables potentially affecting maintenance in zoonotic cycles or affecting transmission rates. T. cruzi and Triatoma spp. DNA was amplified by PCR, using primers targeting several conserved loci. The amplicons were sequenced and used as markers in establishing phylogenetic relationships. Spatial modeling was utilized to overlay vector and parasite geographic distributions with environmental factors in order to illustrate any potential associations.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12503/27280
dc.language.isoen
dc.provenance.legacyDownloads191
dc.subjectCell Biology
dc.subjectMedicine and Health Sciences
dc.subjectParasitology
dc.subjectTrypanosoma cruzi
dc.subjecttriatoma
dc.subjectchagas disease
dc.subjectphylogeography
dc.subjectgis
dc.subjecttexas
dc.titleSpatial phylogeography and correlation between genetic and geographical distance in Trypanosoma cruzi and its vectors of the genus Triatoma from Texas.
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentGraduate School of Biomedical Sciences
thesis.degree.grantorUniversity of North Texas Health Science Center at Fort Worth
thesis.degree.nameMaster of Science

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